EC Number |
General Information |
Reference |
---|
4.2.1.9 | malfunction |
deletion Dilv3A strain requires supplementation with isoleucine and valine for growth |
730702 |
4.2.1.9 | malfunction |
mutants lacking AfIlv3A and ilv3B exhibit reduced levels of virulence in murine infection models |
730702 |
4.2.1.9 | metabolism |
biosynthesis pathway of the branched chain amino acids valine and isoleucine |
-, 732214 |
4.2.1.9 | metabolism |
DHAD is involved in the biosynthetic pathways of L-valine, L-isoleucine, L-leucine, and D-pantothenate, regulation, overview |
-, 715798 |
4.2.1.9 | metabolism |
dihydroxyacid dehydratase, a key enzyme involved in branched-chain amino acid biosynthesis, catalyses the synthesis of 2-oxoacids from dihydroxyacids |
-, 713840, 716148 |
4.2.1.9 | metabolism |
the enzyme is implicated in latex metabolism |
758969 |
4.2.1.9 | physiological function |
complete gene disruption causes partial sterility in both male and female gametophyte phases. Reduced expression of DHAD in knockdown mutants results in a reduction in the accumulation of all three branched-chain amino acid in roots and leads to a shorter root phenotype. The knockdown mutants become hypersensitive to salt stress, not to heavy metal stress |
748324 |
4.2.1.9 | physiological function |
Rv0189c has a role in the survival of Mycobacterium tuberculosis during normal and stress conditions |
-, 716148 |