EC Number   |
kcat/KM Value [1/mMs-1] |
kcat/KM Value Maximum [1/mMs-1] |
Substrate |
Reference |
|---|
   1.14.11.29 | 0.0083 |
- |
O2 |
mutant enzyme T387N, at pH 7.0 and 37°C |
741910 |
| 1.14.11.29 | 0.25 |
- |
O2 |
wild type isoform PHD2, at pH 7.0 and 37°C |
741910 |
| 1.14.11.29 | 0.72 |
- |
hypoxia-inducible factor-L-proline |
N-terminal oxygen degradation domain DALTLLAP402AAGDTIISLDYG mutant F413Y in absence of NaCl, pH 7.0, 37°C |
725653 |
| 1.14.11.29 | 0.94 |
- |
hypoxia-inducible factor-L-proline |
N-terminal oxygen degradation domain DALTLLAP402AAGDTIISLDYG mutant F413Y in presence of 100 mM NaCl, pH 7.0, 37°C |
725653 |
| 1.14.11.29 | 4.76 |
- |
hypoxia-inducible factor-L-proline |
C-terminal oxygen degradation domain DLDLEALAP564YIPADDDFQL mutant M561A/M568A in presence of 100 mM NaCl, pH 7.0, 37°C |
725653 |
| 1.14.11.29 | 5 |
- |
O2 |
mutant enzyme T387A, at pH 7.0 and 37°C |
741910 |
| 1.14.11.29 | 11.7 |
- |
DLDLEALAPYIPADDDFQL |
mutant enzyme T387N, at pH 7.0 and 37°C |
741910 |
| 1.14.11.29 | 18.8 |
- |
hypoxia-inducible factor-L-proline |
C-terminal oxygen degradation domain DLDLEALAP564YIPADDDFQL mutant M561A/M568A in absence of NaCl, pH 7.0, 37°C |
725653 |
| 1.14.11.29 | 25 |
- |
2-oxoglutarate |
mutant enzyme T387N, at pH 7.0 and 37°C |
741910 |
| 1.14.11.29 | 40 |
- |
DLDLEALAPYIPADDDFQL |
wild type isoform PHD2, at pH 7.0 and 37°C |
741910 |
