EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.100 | 3-oxoacyl-[acyl-carrier-protein] reductase |
MDA-MB-231 cell |
- |
735600 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
MDA-MB-231 cell |
- |
741035 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
MDA-MB-231 cell |
low enzyme expression level |
668162 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
MDA-MB-231 cell |
- |
743697 |
1.1.1.188 | prostaglandin-F synthase |
MDA-MB-231 cell |
high expression level |
740999 |
1.1.1.205 | IMP dehydrogenase |
MDA-MB-231 cell |
- |
761611 |
1.1.1.22 | UDP-glucose 6-dehydrogenase |
MDA-MB-231 cell |
- |
760676, 762065 |
1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
MDA-MB-231 cell |
- |
763404 |
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
MDA-MB-231 cell |
- |
761332 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
MDA-MB-231 cell |
- |
741037 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
MDA-MB-231 cell |
- |
285981, 287195, 287199, 287200 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
MDA-MB-231 cell |
breast cancer cell line MDA-MB-231 |
285981 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
MDA-MB-231 cell |
weak activity |
670262 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
MDA-MB-231 cell |
- |
762072 |
1.11.1.8 | iodide peroxidase |
MDA-MB-231 cell |
- |
765648 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
MDA-MB-231 cell |
- |
765516 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
MDA-MB-231 cell |
- |
765516 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
MDA-MB-231 cell |
- |
744594 |
1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
MDA-MB-231 cell |
- |
743380 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
MDA-MB-231 cell |
- |
725955 |
1.14.11.53 | mRNA N6-methyladenine demethylase |
MDA-MB-231 cell |
- |
739559 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
MDA-MB-231 cell |
- |
744782 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
MDA-MB-231 cell |
- |
711677, 764400 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
MDA-MB-231 cell |
- |
758215 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
MDA-MB-231 cell |
low KDM5B expression level |
744657 |
1.14.13.225 | F-actin monooxygenase |
MDA-MB-231 cell |
- |
764398 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
MDA-MB-231 cell |
a breast carcinoma |
685815 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
MDA-MB-231 cell |
breast cancer cell, expresses both the 55-kDa isoform and the 32-kDa truncated isoform of CYP11A1 |
705739 |
1.14.18.6 | 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase |
MDA-MB-231 cell |
- |
743867 |
1.14.19.17 | sphingolipid 4-desaturase |
MDA-MB-231 cell |
- |
744686 |
1.15.1.1 | superoxide dismutase |
MDA-MB-231 cell |
- |
716197 |
1.17.1.4 | xanthine dehydrogenase |
MDA-MB-231 cell |
- |
687917 |
1.17.1.4 | xanthine dehydrogenase |
MDA-MB-231 cell |
low XDH expression and activity |
704789 |
1.3.1.24 | biliverdin reductase |
MDA-MB-231 cell |
- |
740411 |
1.4.3.13 | protein-lysine 6-oxidase |
MDA-MB-231 cell |
- |
687919, 687920, 700903, 713156 |
1.5.1.2 | pyrroline-5-carboxylate reductase |
MDA-MB-231 cell |
- |
762877, 763322 |
1.5.3.17 | non-specific polyamine oxidase |
MDA-MB-231 cell |
- |
764224 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
MDA-MB-231 cell |
- |
713005 |
2.1.1.100 | protein-S-isoprenylcysteine O-methyltransferase |
MDA-MB-231 cell |
- |
704546, 719233, 733780, 734815, 757231, 757874 |
2.1.1.220 | tRNA (adenine58-N1)-methyltransferase |
MDA-MB-231 cell |
- |
721024 |
2.1.1.244 | protein N-terminal methyltransferase |
MDA-MB-231 cell |
low enzyme expression level |
736919 |
2.1.1.319 | type I protein arginine methyltransferase |
MDA-MB-231 cell |
- |
756861 |
2.1.1.321 | type III protein arginine methyltransferase |
MDA-MB-231 cell |
- |
734819 |
2.1.1.348 | mRNA m6A methyltransferase |
MDA-MB-231 cell |
- |
757797 |
2.1.1.361 | [histone H4]-lysine20 N-methyltransferase |
MDA-MB-231 cell |
- |
753133, 754107 |
2.1.1.371 | [histone H3]-lysine27 N-dimethyltransferase |
MDA-MB-231 cell |
- |
758721 |
2.1.1.45 | thymidylate synthase |
MDA-MB-231 cell |
- |
703391, 756651 |
2.1.1.56 | mRNA (guanine-N7)-methyltransferase |
MDA-MB-231 cell |
- |
757896 |
2.1.1.6 | catechol O-methyltransferase |
MDA-MB-231 cell |
- |
702405, 702678 |
2.3.1.108 | alpha-tubulin N-acetyltransferase |
MDA-MB-231 cell |
- |
736879 |
2.3.1.108 | alpha-tubulin N-acetyltransferase |
MDA-MB-231 cell |
invasive breast cancer cells |
719403 |
2.3.1.147 | glycerophospholipid arachidonoyl-transferase (CoA-independent) |
MDA-MB-231 cell |
- |
676922 |
2.3.1.147 | glycerophospholipid arachidonoyl-transferase (CoA-independent) |
MDA-MB-231 cell |
estrogen receptor-negative breast cancer cell |
658381 |
2.3.1.21 | carnitine O-palmitoyltransferase |
MDA-MB-231 cell |
- |
757297 |
2.3.1.225 | protein S-acyltransferase |
MDA-MB-231 cell |
- |
756336 |
2.3.1.258 | N-terminal methionine Nalpha-acetyltransferase NatE |
MDA-MB-231 cell |
- |
740753 |
2.3.1.291 | sphingoid base N-palmitoyltransferase |
MDA-MB-231 cell |
- |
752733 |
2.3.1.5 | arylamine N-acetyltransferase |
MDA-MB-231 cell |
- |
686948, 689073, 702102, 756019, 756372, 756928, 757645, 757700 |
2.3.1.5 | arylamine N-acetyltransferase |
MDA-MB-231 cell |
breast cancer cell line, estrogen receptor (ER)-negative, expression below detection limits in Western blot analysis |
686948 |
2.3.1.85 | fatty-acid synthase system |
MDA-MB-231 cell |
- |
735600, 736065, 737292, 757719 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
MDA-MB-231 cell |
- |
758247 |
2.3.2.26 | HECT-type E3 ubiquitin transferase |
MDA-MB-231 cell |
- |
733626 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
759404 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
736507 |
2.4.1.149 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
706504 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
758992 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
MDA-MB-231 cell |
- |
735901 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
703899, 735590 |
2.4.1.212 | hyaluronan synthase |
MDA-MB-231 cell |
MDA-MB-231 and Hs-578T breast cancer cell line express higher levels of HAS2 mRNA and synthesize higher amounts of HA than breast cancer cell lines with a less aggressive phenotype, like MCF-7. HAS2 is dramatically increased in bone metastases compared to the parental MDA-MB-231 cells |
759182 |
2.4.1.222 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
735881 |
2.4.1.223 | glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
758941 |
2.4.1.224 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase |
MDA-MB-231 cell |
- |
758941 |
2.4.1.225 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase |
MDA-MB-231 cell |
- |
758941 |
2.4.1.255 | protein O-GlcNAc transferase |
MDA-MB-231 cell |
- |
706017 |
2.4.1.50 | procollagen galactosyltransferase |
MDA-MB-231 cell |
- |
725955 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
MDA-MB-231 cell |
- |
735766, 735872, 736436 |
2.4.2.4 | thymidine phosphorylase |
MDA-MB-231 cell |
- |
685914, 701722, 735920 |
2.4.2.64 | tRNA-guanosine34 queuine transglycosylase |
MDA-MB-231 cell |
- |
758996 |
2.4.3.2 | beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase |
MDA-MB-231 cell |
- |
745288 |
2.4.3.6 | N-acetyllactosaminide alpha-2,3-sialyltransferase |
MDA-MB-231 cell |
- |
759169 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
MDA-MB-231 cell |
- |
736910 |
2.5.1.18 | glutathione transferase |
MDA-MB-231 cell |
- |
705056 |
2.5.1.26 | alkylglycerone-phosphate synthase |
MDA-MB-231 cell |
- |
759149 |
2.5.1.59 | protein geranylgeranyltransferase type I |
MDA-MB-231 cell |
- |
759142 |
2.6.1.1 | aspartate transaminase |
MDA-MB-231 cell |
- |
737616 |
2.6.1.52 | phosphoserine transaminase |
MDA-MB-231 cell |
- |
759123 |
2.6.1.64 | glutamine-phenylpyruvate transaminase |
MDA-MB-231 cell |
- |
759123 |
2.7.1.105 | 6-phosphofructo-2-kinase |
MDA-MB-231 cell |
- |
698929, 760902 |
2.7.1.107 | diacylglycerol kinase (ATP) |
MDA-MB-231 cell |
breast cancer cell |
690450 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
MDA-MB-231 cell |
- |
699006 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
MDA-MB-231 cell |
- |
738651 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
MDA-MB-231 cell |
- |
739216 |
2.7.1.183 | glycoprotein-mannosyl O6-kinase |
MDA-MB-231 cell |
- |
762066 |
2.7.1.32 | choline kinase |
MDA-MB-231 cell |
- |
672898, 705894, 723311, 739185 |
2.7.1.32 | choline kinase |
MDA-MB-231 cell |
invasive estrogen receptor-negative cell line |
685941 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
MDA-MB-231 cell |
- |
738106, 738599, 738651, 759475 |
2.7.1.74 | deoxycytidine kinase |
MDA-MB-231 cell |
- |
761315 |
2.7.1.78 | polynucleotide 5'-hydroxyl-kinase |
MDA-MB-231 cell |
- |
703029 |
2.7.10.1 | receptor protein-tyrosine kinase |
MDA-MB-231 cell |
- |
674071 |
2.7.10.2 | non-specific protein-tyrosine kinase |
MDA-MB-231 cell |
- |
761906 |