EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
U-87MG cell |
- |
761406, 761611 |
1.1.1.300 | NADP-retinol dehydrogenase |
U-87MG cell |
- |
762073 |
1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
U-87MG cell |
- |
761976 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
U-87MG cell |
- |
765516 |
1.13.11.34 | arachidonate 5-lipoxygenase |
U-87MG cell |
- |
688512 |
1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
U-87MG cell |
- |
744649 |
1.14.19.17 | sphingolipid 4-desaturase |
U-87MG cell |
- |
744418, 744680 |
1.17.3.2 | xanthine oxidase |
U-87MG cell |
glioma cell |
672905 |
2.1.1.319 | type I protein arginine methyltransferase |
U-87MG cell |
- |
756861 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
U-87MG cell |
- |
702153, 705897, 718566 |
2.1.1.77 | protein-L-isoaspartate(D-aspartate) O-methyltransferase |
U-87MG cell |
- |
702014, 705912 |
2.3.1.256 | N-terminal methionine Nalpha-acetyltransferase NatC |
U-87MG cell |
- |
756860 |
2.3.1.297 | very-long-chain ceramide synthase |
U-87MG cell |
- |
754576 |
2.3.1.299 | sphingoid base N-stearoyltransferase |
U-87MG cell |
- |
754576 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
U-87MG cell |
- |
736889 |
2.3.3.8 | ATP citrate synthase |
U-87MG cell |
- |
704077 |
2.4.1.101 | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
U-87MG cell |
- |
759196 |
2.4.1.11 | glycogen(starch) synthase |
U-87MG cell |
glycolytic glioma cells with active glycogensynthase are sensitive to phosphatase and tensin homolog (PTEN) and inhibitors of phosphatidylinositol-3 kinase and gluconeogenesis |
675727 |
2.4.1.228 | lactosylceramide 4-alpha-galactosyltransferase |
U-87MG cell |
- |
703901 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
U-87MG cell |
- |
685932 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
U-87MG cell |
glioma cell line |
674776 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
U-87MG cell |
- |
736436 |
2.4.2.4 | thymidine phosphorylase |
U-87MG cell |
- |
759610 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
U-87MG cell |
- |
721773 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
U-87MG cell |
up-regulation of hST8Sia III via phosphoinositide 3 kinase/AKT pathway results in the neuronal differentiation of U-87 cells by inducing expression of beta-tubulin III |
677920 |
2.5.1.26 | alkylglycerone-phosphate synthase |
U-87MG cell |
- |
751764 |
2.5.1.46 | deoxyhypusine synthase |
U-87MG cell |
- |
723584 |
2.5.1.59 | protein geranylgeranyltransferase type I |
U-87MG cell |
- |
723013 |
2.7.1.137 | phosphatidylinositol 3-kinase |
U-87MG cell |
- |
688925, 709478 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
U-87MG cell |
- |
761163 |
2.7.1.91 | sphingosine kinase |
U-87MG cell |
- |
703015, 703252 |
2.7.1.94 | acylglycerol kinase |
U-87MG cell |
- |
761230 |
2.7.10.2 | non-specific protein-tyrosine kinase |
U-87MG cell |
- |
693137, 721489 |
2.7.11.13 | protein kinase C |
U-87MG cell |
- |
676323, 723939 |
2.7.11.20 | elongation factor 2 kinase |
U-87MG cell |
glioblastoma cell line |
664502 |
2.7.11.22 | cyclin-dependent kinase |
U-87MG cell |
- |
692997 |
2.7.11.24 | mitogen-activated protein kinase |
U-87MG cell |
- |
703561, 705276 |
2.7.2.3 | phosphoglycerate kinase |
U-87MG cell |
- |
761885 |
2.7.6.2 | thiamine diphosphokinase |
U-87MG cell |
- |
762080 |
2.7.7.19 | polynucleotide adenylyltransferase |
U-87MG cell |
- |
762042 |
2.8.2.17 | chondroitin 6-sulfotransferase |
U-87MG cell |
- |
761061 |
2.8.2.5 | chondroitin 4-sulfotransferase |
U-87MG cell |
- |
761061 |
3.1.3.16 | protein-serine/threonine phosphatase |
U-87MG cell |
Aalpha subunit is expressed at high levels |
654507 |
3.1.3.4 | phosphatidate phosphatase |
U-87MG cell |
- |
716195 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
U-87MG cell |
glioblastoma-astrocytoma, epithelial-like cell line |
694916 |
3.1.3.86 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
U-87MG cell |
- |
749524 |
3.1.31.1 | micrococcal nuclease |
U-87MG cell |
- |
751764 |
3.1.4.11 | phosphoinositide phospholipase C |
U-87MG cell |
- |
691606 |
3.1.4.4 | phospholipase D |
U-87MG cell |
- |
664864 |
3.1.4.4 | phospholipase D |
U-87MG cell |
a glioma cell line |
708012 |
3.1.4.4 | phospholipase D |
U-87MG cell |
astroglioma cell |
664864 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
U-87MG cell |
- |
691859 |
3.2.1.114 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
U-87MG cell |
- |
707745 |
3.2.1.166 | heparanase |
U-87MG cell |
- |
693933, 714936, 715536, 754394 |
3.3.2.9 | microsomal epoxide hydrolase |
U-87MG cell |
- |
732940 |
3.4.14.4 | dipeptidyl-peptidase III |
U-87MG cell |
concurrent expression of mRNA variants DPP III V-I and V-II |
754680 |
3.4.14.5 | dipeptidyl-peptidase IV |
U-87MG cell |
neuroectodermal glioma cell line, proliferating and quiescent populations |
649286 |
3.4.17.21 | Glutamate carboxypeptidase II |
U-87MG cell |
- |
731253, 731257 |
3.4.17.21 | Glutamate carboxypeptidase II |
U-87MG cell |
the level of glutamate carboxypeptidase II protein (GCPII) is regulated by valproic acid, a histone deacetylase (HDAC) inhibitor, through acetylation of lysine residue in the GCPII protein in human astrocytes, U-87MG |
752648 |
3.4.21.109 | matriptase |
U-87MG cell |
- |
717799 |
3.4.22.1 | cathepsin B |
U-87MG cell |
- |
707157, 717228 |
3.4.22.1 | cathepsin B |
U-87MG cell |
a glioblastoma cell line |
710205 |
3.4.22.1 | cathepsin B |
U-87MG cell |
glioblastoma cells |
707967 |
3.4.22.1 | cathepsin B |
U-87MG cell |
glioma cell line |
707558 |
3.4.22.1 | cathepsin B |
U-87MG cell |
upregulation of CatB |
707625 |
3.4.22.15 | cathepsin L |
U-87MG cell |
- |
701145, 711349 |
3.4.22.53 | calpain-2 |
U-87MG cell |
- |
718169 |
3.4.22.59 | caspase-6 |
U-87MG cell |
- |
703561 |
3.4.22.61 | caspase-8 |
U-87MG cell |
no change in activity after irradiation |
664508 |
3.4.24.17 | stromelysin 1 |
U-87MG cell |
astroglioma cells |
708089 |
3.4.24.23 | matrilysin |
U-87MG cell |
- |
683864 |
3.4.24.35 | gelatinase B |
U-87MG cell |
- |
699656, 707452, 708089 |
3.4.24.86 | ADAM 17 endopeptidase |
U-87MG cell |
- |
712612 |
3.4.24.B3 | matrix metalloproteinase-11 |
U-87MG cell |
- |
694496 |
3.4.24.B4 | matrix metalloproteinase-13 |
U-87MG cell |
- |
711163 |
3.4.24.B5 | matrix metalloproteinase-15 |
U-87MG cell |
cancer cell line, low expression of MT2 MMP and expression of MT3 MMP |
651754 |
3.5.1.23 | ceramidase |
U-87MG cell |
- |
754949 |
3.5.1.4 | amidase |
U-87MG cell |
cannabidio is able to induce a concentration dependent increase of FAAH activity in U87 cells. A significantly reduced growth rate is observed in FAAH-overexpressing U87 cells, compared to wild-type controls. FAAH mediates the antitumor activity of cannabidiol |
688512 |
4.1.1.28 | aromatic-L-amino-acid decarboxylase |
U-87MG cell |
- |
716342 |
4.1.3.4 | hydroxymethylglutaryl-CoA lyase |
U-87MG cell |
- |
727926 |
4.2.1.1 | carbonic anhydrase |
U-87MG cell |
- |
700410 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
U-87MG cell |
- |
747508 |
4.3.2.9 | gamma-glutamylcyclotransferase |
U-87MG cell |
- |
735619 |
4.4.1.5 | lactoylglutathione lyase |
U-87MG cell |
- |
709654 |
5.3.99.3 | prostaglandin-E synthase |
U-87MG cell |
constitutive expression of enzyme is associated with increased prostaglandin E2 production and stimulation of growth. Inhibition of enzyme activity and expression block the release of prostaglandin E2 and decrease cellular proliferation. Antiproliferative effects may be overcome by exogenous prostaglandin E2 |
681868 |
5.3.99.5 | thromboxane-A synthase |
U-87MG cell |
- |
705275, 706861 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
U-87MG cell |
- |
703012 |