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Search term: megakaryocyte
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EC Number
Recommended Name
Source Tissue
Commentary
Reference
1.1.1.64
testosterone 17beta-dehydrogenase (NADP+)
megakaryocyte
-
762479
2.4.1.68
glycoprotein 6-alpha-L-fucosyltransferase
megakaryocyte
heavy load of 6FucT
658418
2.7.1.137
phosphatidylinositol 3-kinase
megakaryocyte
primary
640902
2.7.1.154
phosphatidylinositol-4-phosphate 3-kinase
megakaryocyte
-
739146
2.7.1.91
sphingosine kinase
megakaryocyte
-
661509
2.7.10.2
non-specific protein-tyrosine kinase
megakaryocyte
-
490459
2.7.11.12
cGMP-dependent protein kinase
megakaryocyte
MEG-01 cell line
663428
2.7.4.21
inositol-hexakisphosphate 5-kinase
megakaryocyte
-
-
,
737929
3.1.8.1
aryldialkylphosphatase
megakaryocyte
PON1
692441
3.2.1.35
hyaluronoglucosaminidase
megakaryocyte
contains only HYAL2 but not HYAL1
701614
3.4.17.12
carboxypeptidase M
megakaryocyte
megakaryocytic cell progenitor
684066
3.4.21.73
u-Plasminogen activator
megakaryocyte
CD34+ progenitor cells express normal amounts of uPA, while their differentiation into megakaryocytes results in abnormally increased expression of the uPA gene but not the flanking genes for vinculin or calcium/calmodulin-dependent protein kinase IIgamma on chromosome 10. uPA shows extensive colocalization with alpha-granule proteins in both cultured Quebec platelet disease megakaryocytes and platelets, and with plasminogen in Quebec platelet disease platelets
696942
3.4.21.79
granzyme B
megakaryocyte
septic megakaryocytes produce platelets with acutely altered mRNA profiles, and these platelets mediate lymphotoxicity via granzyme B
695511
3.6.5.2
small monomeric GTPase
megakaryocyte
expression of Rap2C may be down-regulated diring the late phase of megakaryocyte differentiation and platelet formation
667846
3.6.5.5
dynamin GTPase
megakaryocyte
dynamin 3 participates in the growth and development of megakaryocytes
697798
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