EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.21 | aldose reductase |
smooth muscle cell |
- |
710793 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
smooth muscle cell |
of arteries |
688464 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
smooth muscle cell |
aortic |
-, 745084 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
smooth muscle cell |
- |
753208, 753289 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
smooth muscle cell |
- |
684777 |
1.3.1.21 | 7-dehydrocholesterol reductase |
smooth muscle cell |
- |
763004 |
2.3.1.26 | sterol O-acyltransferase |
smooth muscle cell |
- |
685979 |
2.3.1.48 | histone acetyltransferase |
smooth muscle cell |
- |
-, 755921 |
2.5.1.59 | protein geranylgeranyltransferase type I |
smooth muscle cell |
primary culture of airway smooth muscle cell |
721258 |
2.7.1.137 | phosphatidylinositol 3-kinase |
smooth muscle cell |
vascular |
710354 |
2.7.1.91 | sphingosine kinase |
smooth muscle cell |
- |
671269 |
2.7.11.11 | cAMP-dependent protein kinase |
smooth muscle cell |
gastric, primary |
660682 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle cell |
- |
693879, 738017, 739538 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle cell |
aortic A7r5 smooth muscle cells |
722222 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle cell |
vascular |
662462 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle cell |
vascular, aortic |
663195 |
2.7.11.13 | protein kinase C |
smooth muscle cell |
pulmonary cell line |
662271 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle cell |
- |
684356 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle cell |
primary cultured cells |
740727 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
smooth muscle cell |
- |
760351 |
2.7.12.2 | mitogen-activated protein kinase kinase |
smooth muscle cell |
airway |
679153 |
2.7.12.2 | mitogen-activated protein kinase kinase |
smooth muscle cell |
bronchial airway |
679153 |
3.1.3.16 | protein-serine/threonine phosphatase |
smooth muscle cell |
- |
709072 |
3.1.3.48 | protein-tyrosine-phosphatase |
smooth muscle cell |
- |
709960 |
3.1.3.5 | 5'-nucleotidase |
smooth muscle cell |
- |
678104, 715146, 750719 |
3.1.3.53 | [myosin-light-chain] phosphatase |
smooth muscle cell |
- |
731103 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
smooth muscle cell |
of central cavernous arteries |
671011 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle cell |
- |
670025 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle cell |
isoform PDE5 protein level is strongly regulated by the mitotic activity of cells |
667433 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle cell |
of central cavernous arteries, phosphodiesterase 5 |
671011 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle cell |
PDE5 protein levels are strongly regulated by the mitotic activity of the smooth muscle cells, they are increased in quiescent, contractile myometrial cultures, and conditions in which proliferation is inhibited |
667433 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
smooth muscle cell |
- |
750336 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
smooth muscle cell |
of central cavernous arteries |
671011 |
3.4.15.1 | peptidyl-dipeptidase A |
smooth muscle cell |
from aorta, extracellular ACE binds to smooth muscle cells, overview |
709149 |
3.4.17.23 | angiotensin-converting enzyme 2 |
smooth muscle cell |
- |
679704, 681180 |
3.4.21.20 | cathepsin G |
smooth muscle cell |
- |
731354 |
3.4.21.37 | leukocyte elastase |
smooth muscle cell |
neonatal, aortic |
707071 |
3.4.21.5 | thrombin |
smooth muscle cell |
aortic |
683019 |
3.4.21.73 | u-Plasminogen activator |
smooth muscle cell |
- |
707951 |
3.4.21.73 | u-Plasminogen activator |
smooth muscle cell |
airway |
707892 |
3.4.21.75 | Furin |
smooth muscle cell |
- |
681918 |
3.4.21.79 | granzyme B |
smooth muscle cell |
- |
709759 |
3.4.21.79 | granzyme B |
smooth muscle cell |
perforin-independent expression |
679007 |
3.4.22.27 | cathepsin S |
smooth muscle cell |
SMC, vascular, from aorta |
667140 |
3.4.22.38 | cathepsin K |
smooth muscle cell |
- |
708450 |
3.4.24.15 | thimet oligopeptidase |
smooth muscle cell |
ileum, longitudinal and circular |
683961 |
3.4.24.16 | neurolysin |
smooth muscle cell |
ileum, longitudinal and circular |
683961 |
3.4.24.24 | gelatinase A |
smooth muscle cell |
- |
717633, 754999 |
3.4.24.35 | gelatinase B |
smooth muscle cell |
transfected with a construct expressing enzyme. Enzyme overexpressing cells show a significantly reduced collagen gel contraction |
668176 |
3.4.24.65 | macrophage elastase |
smooth muscle cell |
airway |
708452 |
3.4.24.71 | endothelin-converting enzyme 1 |
smooth muscle cell |
aortic, determination of enzyme expression by immunohistochemical analysis using a combination of ECE-1 isoform-specific antibodies, expression of isozyme ECE-1a |
683440 |
3.4.24.79 | pappalysin-1 |
smooth muscle cell |
- |
683504 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
smooth muscle cell |
aortic |
708193 |
3.4.24.81 | ADAM10 endopeptidase |
smooth muscle cell |
- |
752839 |
3.4.24.82 | ADAMTS-4 endopeptidase |
smooth muscle cell |
- |
755457 |
3.4.24.86 | ADAM 17 endopeptidase |
smooth muscle cell |
- |
753291 |
3.4.24.B11 | ADAMTS1 endopeptidase |
smooth muscle cell |
- |
755146 |
3.4.24.B12 | ADAMTS5 endopeptidase |
smooth muscle cell |
in bronchi and pancreatic ducts, constitutive Adamts5 expression in adult tissue. Expression of Adamts5 during neuromuscular development and in smooth muscle cells coincides with the broadly distributed proteoglycan versican, an ADAMTS5 substrate |
692482 |
3.4.24.B7 | matrix metalloproteinase-26 |
smooth muscle cell |
from coronary artery or from prostate tissue and associated blood vessels |
710794 |
3.6.1.5 | apyrase |
smooth muscle cell |
- |
-, 718543 |
3.6.1.6 | nucleoside diphosphate phosphatase |
smooth muscle cell |
- |
718543 |
3.6.5.2 | small monomeric GTPase |
smooth muscle cell |
- |
720356, 734348 |
3.6.5.2 | small monomeric GTPase |
smooth muscle cell |
microvascular |
720356 |
4.4.1.5 | lactoylglutathione lyase |
smooth muscle cell |
medial, high expression level |
729179 |
4.6.1.2 | guanylate cyclase |
smooth muscle cell |
- |
690364, 691656, 692585 |
4.6.1.2 | guanylate cyclase |
smooth muscle cell |
primary aortic smooth muscle cells |
691841 |
4.6.1.2 | guanylate cyclase |
smooth muscle cell |
vascular |
693087, 693256 |
5.3.99.3 | prostaglandin-E synthase |
smooth muscle cell |
- |
749371 |
5.3.99.4 | prostaglandin-I synthase |
smooth muscle cell |
- |
702474, 748544, 749211 |
6.2.1.15 | arachidonate-CoA ligase |
smooth muscle cell |
aortic |
715838 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
smooth muscle cell |
aortic, levels of isozymes ACSL1, ACSL3, and ACSL5, overview |
715838 |