EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
smooth muscle |
mRNA expression |
692959 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
smooth muscle |
of the vas deferens and penile blood vessels |
655349 |
1.1.1.21 | aldose reductase |
smooth muscle |
- |
711762 |
1.1.1.21 | aldose reductase |
smooth muscle |
vascular cell |
668380 |
1.1.1.21 | aldose reductase |
smooth muscle |
vascular cells |
669468 |
1.1.1.284 | S-(hydroxymethyl)glutathione dehydrogenase |
smooth muscle |
- |
763729 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
smooth muscle |
- |
440226 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
smooth muscle |
isozyme NOS3 |
673804 |
1.17.3.2 | xanthine oxidase |
smooth muscle |
vascular |
688146 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
smooth muscle |
- |
688446 |
1.3.1.24 | biliverdin reductase |
smooth muscle |
pulmonary arterial smooth muscle cell |
724921 |
1.4.3.13 | protein-lysine 6-oxidase |
smooth muscle |
- |
391742, 684889 |
1.4.3.13 | protein-lysine 6-oxidase |
smooth muscle |
LOXL, lamia propria and straited border, not of Goblet cells |
659751 |
1.4.3.13 | protein-lysine 6-oxidase |
smooth muscle |
neural crest- and mesoderm-derived smooth muscle |
698112 |
1.4.3.13 | protein-lysine 6-oxidase |
smooth muscle |
nucleus |
391742 |
1.4.3.4 | monoamine oxidase |
smooth muscle |
of duodenum, lung, blood vessels, spleen |
655721 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
smooth muscle |
- |
671217 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
smooth muscle |
bilirubin concentration-dependently reduces NADPH oxidase-dependent superoxide production stimulated by angiotensin II in vascular smooth muscle cells |
687050 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
smooth muscle |
cultured aortic smooth muscle cell |
684269 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
smooth muscle |
GAMT was highly expressed in perivascular pericytes and smooth muscle cells after birth |
757807 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
smooth muscle |
- |
486621 |
2.3.1.50 | serine C-palmitoyltransferase |
smooth muscle |
- |
487177 |
2.3.2.26 | HECT-type E3 ubiquitin transferase |
smooth muscle |
- |
727872 |
2.4.1.109 | dolichyl-phosphate-mannose-protein mannosyltransferase |
smooth muscle |
- |
723102 |
2.5.1.57 | N-acylneuraminate-9-phosphate synthase |
smooth muscle |
- |
637818 |
2.7.1.107 | diacylglycerol kinase (ATP) |
smooth muscle |
- |
640381 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
smooth muscle |
aortic |
640742, 640743 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
smooth muscle |
tracheal smooth muscle |
694257 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
smooth muscle |
bronchial and cervical, moderate expression of PI3K-C2alpha |
645046 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
smooth muscle |
isozyme PI3K-C2alpha |
645046 |
2.7.1.91 | sphingosine kinase |
smooth muscle |
gracilis muscle resistance artery. Pressure-dependent activation and translocation of isoform Sk1 by ERK1/2 is critically dependent on its serine225 phosphorylation site |
701973 |
2.7.10.1 | receptor protein-tyrosine kinase |
smooth muscle |
- |
672957, 673210 |
2.7.10.1 | receptor protein-tyrosine kinase |
smooth muscle |
aortic |
660727 |
2.7.11.11 | cAMP-dependent protein kinase |
smooth muscle |
portal vein smooth muscle myocyte |
662708 |
2.7.11.11 | cAMP-dependent protein kinase |
smooth muscle |
pulmonary arterial |
660660 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
- |
661497, 661575, 671256, 704490 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
corpus cavernosum smooth muscle, high expression of isozymes PKG-1alpha and PKG-1beta, corpus cavernosum smooth muscle of diabetic rabbits show reduced expression of isozyme PKG-1alpha |
660671 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
e.g. aortic |
660710 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
gastric, primary |
660682 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
high expression levels of cGKI in vascular and intestinal smooth muscle, both isozymes in cardiovascular muscle, fibromuscular stroma |
673462 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
pulmonary arterial |
660665 |
2.7.11.12 | cGMP-dependent protein kinase |
smooth muscle |
pulmonary artery |
674575 |
2.7.11.13 | protein kinase C |
smooth muscle |
no isozyme beta, high expression of isozyme delta |
661849 |
2.7.11.13 | protein kinase C |
smooth muscle |
pulmonary arterial |
660666 |
2.7.11.15 | beta-adrenergic-receptor kinase |
smooth muscle |
- |
644999 |
2.7.11.15 | beta-adrenergic-receptor kinase |
smooth muscle |
DDT-MF2 smooth muscle cells derived from ductus deferens leiomyosarcoma |
645017 |
2.7.11.16 | G-protein-coupled receptor kinase |
smooth muscle |
airway, GRK5 |
660667 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
- |
490797, 490801, 491268, 640624, 640632, 640634, 640635, 640645, 640647, 640648, 640649, 640652, 640653, 640655, 640659, 640661, 660857, 661729, 671222, 675623, 686927, 687732, 707084, 740060, 740266 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
airway |
688705 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
arterial |
640624, 640632 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
cardiac |
686119 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
from bladder |
684333 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
from gizzard |
684910 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
from stomach |
684910 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
long (220 kDa) and short (130 kDa) MLCK isozymes |
-, 740289 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
long isozyme L-MLCK and short isozyme S-MLCK |
672984 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
smMLCK expresses in almost every tissue, including smooth muscles |
708142 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
specific isozyme |
663442 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
specific smooth muscle isozyme smMLCK encoded by gene MLCK2 |
675068 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
the abundance of active MLCK, which is tightly associated with the contractile apparatus, is low relative to that of smooth muscle myosin |
740823 |
2.7.11.18 | myosin-light-chain kinase |
smooth muscle |
uterus, trachea, aorta, ileum, gizzard |
491268 |
2.7.11.24 | mitogen-activated protein kinase |
smooth muscle |
- |
692738 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
smooth muscle |
- |
687732, 703277 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
smooth muscle |
pulmonary arterial |
692195 |
2.7.3.3 | arginine kinase |
smooth muscle |
high ecpression of PyAK4 |
760431 |
2.7.4.24 | diphosphoinositol-pentakisphosphate 1-kinase |
smooth muscle |
- |
662914 |
2.7.7.41 | phosphatidate cytidylyltransferase |
smooth muscle |
- |
661820 |
3.1.1.7 | acetylcholinesterase |
smooth muscle |
- |
752242 |
3.1.1.8 | cholinesterase |
smooth muscle |
- |
752242 |
3.1.3.16 | protein-serine/threonine phosphatase |
smooth muscle |
- |
134595, 666435, 679081 |
3.1.3.16 | protein-serine/threonine phosphatase |
smooth muscle |
isozyme PP1delta |
664705 |
3.1.3.53 | [myosin-light-chain] phosphatase |
smooth muscle |
- |
677994, 679143, 699117, 700149, 702129, 704517, 713963, 749533, 751394, 751951 |
3.1.3.53 | [myosin-light-chain] phosphatase |
smooth muscle |
from femoral arteries |
646366 |
3.1.3.53 | [myosin-light-chain] phosphatase |
smooth muscle |
phasic portal vein and vas deferens smooth muscles |
646356 |
3.1.3.55 | caldesmon-phosphatase |
smooth muscle |
smooth muscle neoplasm |
732232 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
smooth muscle |
- |
694494 |
3.1.4.1 | phosphodiesterase I |
smooth muscle |
- |
713998 |
3.1.4.11 | phosphoinositide phospholipase C |
smooth muscle |
- |
692201 |
3.1.4.11 | phosphoinositide phospholipase C |
smooth muscle |
iris |
285226 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle |
presence of isoform PDE5 in smooth muscle of the clitoral erectile tissue |
670983 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle |
smooth muscle specific expression of PDE5A3 |
649549 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
smooth muscle |
splice variant PDE5A3 is specific to smooth muscle |
679401 |
3.2.1.18 | exo-alpha-sialidase |
smooth muscle |
aortic smooth muscle |
695452 |
3.3.2.10 | soluble epoxide hydrolase |
smooth muscle |
- |
663275 |
3.3.2.10 | soluble epoxide hydrolase |
smooth muscle |
of arteriole |
683721 |
3.4.11.2 | membrane alanyl aminopeptidase |
smooth muscle |
arterial smooth muscle |
683811 |
3.4.14.2 | dipeptidyl-peptidase II |
smooth muscle |
uterine myometrium |
650796 |
3.4.16.5 | carboxypeptidase C |
smooth muscle |
vascular |
647190 |
3.4.17.3 | lysine carboxypeptidase |
smooth muscle |
- |
670291 |
3.4.21.122 | transmembrane protease serine 2 |
smooth muscle |
- |
755193 |
3.4.21.35 | tissue kallikrein |
smooth muscle |
- |
696531 |
3.4.21.5 | thrombin |
smooth muscle |
- |
701159 |
3.4.21.5 | thrombin |
smooth muscle |
primary culture of tracheal smooth muscle cell |
667554 |
3.4.22.26 | cancer procoagulant |
smooth muscle |
- |
668476 |
3.4.22.27 | cathepsin S |
smooth muscle |
- |
697361, 699142 |
3.4.22.41 | cathepsin F |
smooth muscle |
expressed at the lowest level in muscles |
753610 |
3.4.22.52 | calpain-1 |
smooth muscle |
- |
644005, 707281 |
3.4.22.53 | calpain-2 |
smooth muscle |
- |
644005 |
3.4.22.61 | caspase-8 |
smooth muscle |
- |
695963 |
3.4.24.24 | gelatinase A |
smooth muscle |
- |
752865 |