EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
uterine endometrium |
the enzyme is expressed mainly in the glandular epithelium, enzyme activity during the oestrous cycle and early pregnancy, overview |
670868 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
uterine endometrium |
HSDB1 transcript abundance in the endometrium and myometrium remain at the same level during the examined days of pregnancy. After luteolysis both endometrial and myometrial HSD3B1 expression wane |
725807 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
uterine endometrium |
- |
696570 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
uterine endometrium |
- |
700189, 737453, 739860, 741454 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
uterine endometrium |
epithelium |
670023 |
1.1.1.188 | prostaglandin-F synthase |
uterine endometrium |
- |
-, 389447, 725083, 740353, 741012, 741357 |
1.1.1.188 | prostaglandin-F synthase |
uterine endometrium |
at oestrus and mid and late phases of pseudopregnancy |
726469 |
1.1.1.188 | prostaglandin-F synthase |
uterine endometrium |
epithelial |
389450 |
1.1.1.188 | prostaglandin-F synthase |
uterine endometrium |
the bovine endometrium produces huge amounts of PGF2alpha |
741357 |
1.1.1.189 | prostaglandin-E2 9-reductase |
uterine endometrium |
- |
657211, 697637 |
1.1.1.189 | prostaglandin-E2 9-reductase |
uterine endometrium |
high expression of conceptus and endometrial terminal CBR1 after initiation of blastocyst attachment suggest its involvement in early placentation |
697792 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
uterine endometrium |
- |
287212 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
uterine endometrium |
in females |
287209 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
uterine endometrium |
- |
287206, 686263 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
uterine endometrium |
endometrial 17beta-hydroxysteroid dehydrogenase activity is decreased on days 15-16 in pregnant and cyclic pigs compared with the preceding days |
762366 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
uterine endometrium |
endometrial carcinoma |
287179, 287189 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
uterine endometrium |
moderate expression, epithelial cells and stromal cells |
685803 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
uterine endometrium |
proliferative |
287179 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
uterine endometrium |
secretory |
287179, 287189 |
1.1.1.95 | phosphoglycerate dehydrogenase |
uterine endometrium |
- |
701170 |
1.11.1.8 | iodide peroxidase |
uterine endometrium |
TPO is expressed at gene and protein levels in endometrium and placenta, expression is mainly localized to glandular and luminal epithelial cells in the endometrium |
764516 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
uterine endometrium |
epithelium |
657496 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
uterine endometrium |
- |
713952, 728342 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
uterine endometrium |
- |
697628, 701168 |
1.21.99.3 | thyroxine 5-deiodinase |
uterine endometrium |
of nonpregnant human uteri |
659569 |
1.6.2.4 | NADPH-hemoprotein reductase |
uterine endometrium |
- |
288559 |
1.8.3.2 | thiol oxidase |
uterine endometrium |
- |
393065 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
uterine endometrium |
- |
752498 |
2.4.1.133 | xylosylprotein 4-beta-galactosyltransferase |
uterine endometrium |
- |
736177 |
2.4.1.17 | glucuronosyltransferase |
uterine endometrium |
isozyme UGT2B7 |
659571 |
2.4.1.212 | hyaluronan synthase |
uterine endometrium |
- |
721933 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
uterine endometrium |
beta1, 4-GalT-I iss highly expressed in endometrium during implantation window |
719575 |
2.4.3.6 | N-acetyllactosaminide alpha-2,3-sialyltransferase |
uterine endometrium |
- |
759047 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
uterine endometrium |
PI3Kgamma, small amounts |
710598 |
2.7.1.3 | ketohexokinase |
uterine endometrium |
expression of ketohexokinase mRNA is greater from day 9 through 17 of pregnancy compared to the corresponding days of the estrous cycle. There is an increase in expression of KHK mRNA through day 85, with peaks at days 30 and 85. Ketohexokinase protein is only detectable in GE of the endometrium at day 30 of pregnancy |
758874 |
2.7.12.2 | mitogen-activated protein kinase kinase |
uterine endometrium |
- |
689072 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
uterine endometrium |
- |
644378 |
2.8.2.15 | steroid sulfotransferase |
uterine endometrium |
- |
725045 |
2.8.2.2 | alcohol sulfotransferase |
uterine endometrium |
- |
694547, 738296 |
2.8.2.4 | estrone sulfotransferase |
uterine endometrium |
- |
691580, 695086 |
2.8.2.4 | estrone sulfotransferase |
uterine endometrium |
healthy and hyperplasic endometrium |
693884 |
3.1.3.2 | acid phosphatase |
uterine endometrium |
- |
663765 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
uterine endometrium |
- |
694494 |
3.1.3.9 | glucose-6-phosphatase |
uterine endometrium |
- |
134945 |
3.1.6.2 | steryl-sulfatase |
uterine endometrium |
- |
716213 |
3.3.2.10 | soluble epoxide hydrolase |
uterine endometrium |
exclusively cytosolic |
662565 |
3.3.2.9 | microsomal epoxide hydrolase |
uterine endometrium |
regulation of mEH during the menstrual cycle: during the first half mEH expression is low, increases during the second half and reaches highest levels during pregnancy, immunohistochemical analysis, overview |
709573 |
3.4.11.3 | cystinyl aminopeptidase |
uterine endometrium |
- |
35904 |
3.4.14.4 | dipeptidyl-peptidase III |
uterine endometrium |
- |
683562 |
3.4.17.23 | angiotensin-converting enzyme 2 |
uterine endometrium |
- |
695087 |
3.4.21.120 | oviductin |
uterine endometrium |
it is speculated that receptors for hamster oviductin-1 are present at the apical cell surface of endometrial cells and that implantation of the developing blastocyst into the uterine wall is possible only following downregulation of these receptors |
668865 |
3.4.21.34 | plasma kallikrein |
uterine endometrium |
the kallikrein-kininogen-kinin system is biologically active during establishment of pregnancy in the pig |
667900 |
3.4.21.73 | u-Plasminogen activator |
uterine endometrium |
- |
708237 |
3.4.21.B26 | proprotein convertase 5 |
uterine endometrium |
- |
731899 |
3.4.21.B26 | proprotein convertase 5 |
uterine endometrium |
high enzyme expression level during receptive phase |
731128 |
3.4.21.B26 | proprotein convertase 5 |
uterine endometrium |
the enzyme is up-regulated in the human endometrium specifically at the time of epithelial receptivity |
732515 |
3.4.22.27 | cathepsin S |
uterine endometrium |
- |
668394 |
3.4.22.34 | Legumain |
uterine endometrium |
- |
700314 |
3.4.22.43 | cathepsin V |
uterine endometrium |
- |
731573 |
3.4.23.B1 | napsin |
uterine endometrium |
- |
753774, 754263 |
3.4.24.23 | matrilysin |
uterine endometrium |
- |
708164, 710536 |
3.4.24.23 | matrilysin |
uterine endometrium |
MMP-7 levels in eutopic and ectopic endometriose, overview. MMP-7 expression levels are significantly higher in the endometrial epithelial cells from women with deep infiltrating endometriosis compared with those isolated from the endometria of patients with only superficial peritoneal endometriosis, uterine myomas or normal endometrium, in the proliferative, late secretory and menstrual phases. MMP-7 protein expression is detected in the ectopic endometrial epithelial cells of samples of deep infiltrating endometriosis, of ovarian endometriosis, of black peritoneal lesions, and of red peritoneal lesions. MMP-7 protein expression in epithelial cells is significantly higher in red peritoneal lesions compared with that of deep infiltrating endometriosis, ovarian endometriosis and black peritoneal lesions, in all phases of the menstrual cycle, quantitative real-time RT-PCR and immunohistochemical analysis, overview |
708674 |
3.4.24.24 | gelatinase A |
uterine endometrium |
- |
752865 |
3.4.24.24 | gelatinase A |
uterine endometrium |
eutopic, and ectopic, ovarian |
755131 |
3.4.24.35 | gelatinase B |
uterine endometrium |
- |
708232 |
3.4.24.B7 | matrix metalloproteinase-26 |
uterine endometrium |
MMP-26 mRNA is evenly distributed in all glandular epithelial cells and luminal epithelial cells but is absent in the stroma. The amount of MMP-26 mRNA is greater in samples at day 5 in an artificial cycle of progesterone addition than at day 7 in an artificial cycle of progesterone addition |
687046 |
4.1.1.17 | ornithine decarboxylase |
uterine endometrium |
ODC1 is highly expressed in endometrial cancers |
749114 |
4.2.1.1 | carbonic anhydrase |
uterine endometrium |
- |
33547 |
4.2.1.1 | carbonic anhydrase |
uterine endometrium |
carbonic anhydrase XIII |
679413 |
5.3.99.2 | Prostaglandin-D synthase |
uterine endometrium |
of cyclic, pregnant, and pseudopregnant rats. Expression of prostaglandin D synthase or prostacyclin synthase are not influenced by the estrous cycle. Prostaglandion D synthase expression is high during early and maximal at the end of pregnancy. During pseudopregnancy, enzyme is increased in time-dependent manner and maximal at day 5 |
681106 |
5.3.99.3 | prostaglandin-E synthase |
uterine endometrium |
enzyme protein is elevated in the endometrium during spontaneous term labour and after estradiol treatment. Enzyme is localized to endometrial stromal cells |
679515 |
5.3.99.4 | prostaglandin-I synthase |
uterine endometrium |
of cyclic, pregnant, and pseudopregnant rats. Expression of prostacyclin synthase is increases during early pregnancy and decreases gradually from day 5.5 to 6.5. Later during pregnancy, expression of enzyme is maximal on day 12 and decrease to the end of pregnancy. During pseudopregnancy, both prostaglandin D synthase and prostacyclin synthase are increased in a time-dependent manner and are maximal at day 5. Both enzymes are found in luminal as well as glandular epithelial cells and in stroma during late pregnancy |
681106 |
6.1.1.2 | tryptophan-tRNA ligase |
uterine endometrium |
caruncular endometrial tissues of unilaterally pregnant ewes at implantation (day 16) and post-implantation (day 20) periods. WARS protein expression increased in caruncular tissues of the gravid uterine horns compared with the non-gravid uterine horns on days 16 and 20 of pregnancy. On day 16 of pregnancy, there are no differences in WARS mRNA expression between the gravid and non-gravid uterine horns but expression of the gene is higher in the gravid uterine horns when compared with the non-gravid uterine horns on day 20 of pregnancy |
745083 |