EC Number |
Source Tissue |
Reference |
---|
1.8.4.11 | alveolar macrophage |
- |
686598 |
1.8.4.11 | blood |
- |
686598 |
1.8.4.11 | blood |
maximal expression level of MsrA in kidney and liver, followed by heart, lung, brain, skeletal muscle, retina, testis, bone marrow, and blood |
763918 |
1.8.4.11 | bone marrow |
high MsrA expression level |
668581 |
1.8.4.11 | bone marrow |
maximal expression level of MsrA in kidney and liver, followed by heart, lung, brain, skeletal muscle, retina, testis, bone marrow, and blood |
763918 |
1.8.4.11 | brain |
- |
393074, 657754, 658213, 668092, 668357, 698124, 700465 |
1.8.4.11 | brain |
a knockout mouse strain of the methionine sulfoxide reductase A gene (MsrA-/-) causes an enhanced neurodegeneration in brain hippocampus relative to its wild-type control mouse brain. Deficiency in MsrA activity fosters oxidative-stress that is manifested by the accumulation of faulty proteins (via methionine oxidation), deposition of aggregated proteins, and premature brain cell death |
686580 |
1.8.4.11 | brain |
calf, sulindac reducing activity |
658212 |
1.8.4.11 | brain |
maximal expression level of MsrA in kidney and liver, followed by heart, lung, brain, skeletal muscle, retina, testis, bone marrow, and blood |
763918 |
1.8.4.11 | brain |
MsrA |
658217 |