EC Number |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
---|
1.1.1.88 | -999 |
- |
after a dietary intake of docosahexaenoic acid ethyl ester (DHA-EE) brain HMG-CoA reductase activity and brain cholesterol content significantly increases with age. Hepatic HMG-CoA reductase activity and the cholesterol content of both adult and aged mice are reduced in DHA-EE diet groups compared with linoleic acid ethyl ester |
688564 |
1.1.1.88 | 0.011 |
- |
H381A-mutant, mevalonate acylation |
287502 |
1.1.1.88 | 0.029 |
- |
H381N-mutant, mevalonate acylation |
287502 |
1.1.1.88 | 0.041 |
- |
H381Q-mutant, mevalonate acylation |
287502 |
1.1.1.88 | 0.091 |
- |
H381K-mutant, mevalonate acylation |
287502 |
1.1.1.88 | 0.163 |
- |
mevalonate acylation |
287495 |
1.1.1.88 | 0.17 |
- |
mevalonate acylation |
287495 |
1.1.1.88 | 0.922 |
- |
wild-type enzyme, [14C]-mevalonate acylation |
287503 |
1.1.1.88 | 1.203 |
- |
S871A [14C]-mevalonate acylation |
287503 |
1.1.1.88 | 2.7 |
- |
reverse reaction, pH 7.9, 30°C |
723092 |