EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.13.11.B6 | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid + O2 |
gamma-linoleate is oxidized at C-9, C-11, and C-13 |
Nakataea oryzae CBS 288.54 |
? |
- |
? |
1.13.11.B6 | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid + O2 |
i.e. alpha-linoleic acid |
Lasiodiplodia theobromae |
(9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid + (9Z,12Z,15Z)-9-hydroxy-10-oxooctadeca-12,15-dienoic acid |
- |
? |
1.13.11.B6 | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid + O2 |
i.e. alpha-linoleic acid |
Lasiodiplodia theobromae 2334 |
(9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid + (9Z,12Z,15Z)-9-hydroxy-10-oxooctadeca-12,15-dienoic acid |
- |
? |
1.13.11.B6 | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid + O2 |
i.e. alpha-linoleic acid |
Lasiodiplodia theobromae CBS 117454 |
(9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid + (9Z,12Z,15Z)-9-hydroxy-10-oxooctadeca-12,15-dienoic acid |
- |
? |
1.13.11.B6 | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid + O2 |
i.e. alpha-linoleic acid |
Lasiodiplodia theobromae CBS 122127 |
(9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoic acid + (9Z,12Z,15Z)-9-hydroxy-10-oxooctadeca-12,15-dienoic acid |
- |
? |
1.13.11.B6 | 1,2-di-O-alpha-linolenoyl-3-O-beta-D-galactopyranosyl-sn-glycerol + O2 |
low activity with the wild-type enzyme, no activity with mutant A562G |
Zea mays |
? |
- |
? |
1.13.11.B6 | 2-linoleoyl-sn-glycero-3-phosphorylcholine + O2 |
low activity of wild-type and A562G mutant. The wild-type enzyme predominantly produces (13S)-hydroperoxide. The A562G mutant form possesses lesser regio- and stereospecificity during the dioxygenation of lysoPC. It produces 28% of (10E,12Z)-9-hydroperoxide and 30% of (9Z,11E)-13-hydroperoxide along with 41% of (all-E)-hydroperoxides. While 9-hydroperoxide is present mainly (61%) as S-enantiomer, (9Z,11E)-13-hydroperoxide is nearly racemic |
Zea mays |
? |
- |
? |
1.13.11.B6 | 2-linoleoyl-sn-glycero-3-phosphorylcholine + O2 |
the wild-type ZmLOX produces predominantly (13S)-hydroperoxide. In contrast, the A562G mutant produces excessively (9S)-hydroperoxide. The oxidation of 2-linoleoyl-sn-glycero-3-phosphorylcholine exhibits the limited regio- and stereospecificity. But the A562G mutant form possesses lesser regio- and stereospecificity |
Zea mays |
? |
- |
? |
1.13.11.B6 | all-cis-9,12,15-octadecatrienoic acid + O2 |
i.e. alpha-linoleic acid |
Lasiodiplodia theobromae |
(9R)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoic acid + 9-hydroxy-10-oxo-(12Z,15Z)-octadecadienoic acid |
- |
? |
1.13.11.B6 | all-cis-9,12,15-octadecatrienoic acid + O2 |
i.e. alpha-linoleic acid |
Lasiodiplodia theobromae 2334 |
(9R)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoic acid + 9-hydroxy-10-oxo-(12Z,15Z)-octadecadienoic acid |
- |
? |