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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynicotine + H2O + O2 the enzyme catalyzes the oxidation of (S)-6-hydroxynicotine to 6-hydroxypseudooxynicotine during microbial catabolism of nicotine Paenarthrobacter nicotinovorans 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynicotine + H2O + O2 the enzyme is essential for nicotine or (S)-6-hydroxynicotine degradation Shinella sp. 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynicotine + H2O + O2 the enzyme is involved in degradation of nicotine Ochrobactrum sp. SJY1 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynicotine + H2O + O2 the enzyme converts (S)-6-hydroxynicotine into 6-hydroxy-N-methylmyosmine which then spontaneously hydrolyzes into 6-hydroxypseudooxynicotine. (S)-6-Hydroxynicotine is the preferred substrate in vivo. The enzyme shows no activities toward the R enantiomer of nicotine or 6-hydroxynicotine Shinella sp. 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynicotine + H2O + O2 - Sphingomonas melonis TY 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynicotine + H2O + O2 - Agrobacterium tumefaciens S33 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-6-hydroxynornicotine + H2O + O2 - Paenarthrobacter nicotinovorans ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-nicotine + H2O + O2 - Paenarthrobacter nicotinovorans N-methylmyosmine + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-nicotine + H2O + O2 the enzyme converts (S)-nicotine into N-methylmyosmine, which spontaneously hydrolyzes into pseudooxynicotine Shinella sp. N-methylmyosmine + H2O2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.5(S)-nicotine + H2O + O2 N-methyl-myosmine, which is nonenzymatically hydrolyzed to pseudooxynicotine. The flavoenzyme preferentially oxidizes tertiary amines with an efficient reductive half-reaction and a very slow oxidative half-reaction when O2 is the oxidizing substrate, suggesting that the true oxidizing agent is unknown Pseudomonas putida N-methylmyosmine + H2O2 - ?
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