EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.391 | 12alpha-hydroxy-3-oxo-5-beta-cholan-24-oic acid + NADH + H+ |
- |
Eggerthella lenta |
3beta,12alpha-dihydroxy-5-beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 12alpha-hydroxy-3-oxo-5-beta-cholan-24-oic acid + NADH + H+ |
- |
Eggerthella lenta ATCC 25559 |
3beta,12alpha-dihydroxy-5-beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,12-dioxo-5-beta-cholan-24-oic acid + NADH + H+ |
- |
[Clostridium] innocuum |
3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,12-dioxo-5-beta-cholan-24-oic acid + NADH + H+ |
- |
[Clostridium] innocuum D1144/3 |
3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,12-dioxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,12-dioxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
[Clostridium] innocuum |
3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,12-dioxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
[Clostridium] innocuum D1144/3 |
3beta-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3,7-dioxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
Blautia producta |
3beta-hydroxy-7-oxo-5beta-cholan-24-oic acid + NAD+ |
- |
? |
1.1.1.391 | 3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
i.e. isochenodeoxycholic acid |
Homo sapiens |
7alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
? |
1.1.1.391 | 3beta,7beta-dihydroxy-5beta-cholan-24-oic acid + NAD+ |
substrate docking of isoursodeoxycholic acid to the active site of a three-dimensional model of human class I gammagamma alcohol dehydrogenase reveals that the ADH gammagamma isozyme is the iso bile acid 3beta-hydroxysteroid dehydrogenase present in human liver cytosol, with NAD+ as a cofactor, but ethanol is the preferred substrate |
Homo sapiens |
7beta-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ |
- |
? |