EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.2 | (+)-camphorquinone + NADPH |
- |
Homo sapiens |
? + NADP+ |
- |
? |
1.1.1.2 | (+)-camphorquinone + NADPH |
- |
Sus scrofa |
? + NADP+ |
- |
? |
1.1.1.2 | (-)-camphorquinone + NADPH |
relative activity 2% |
Sus scrofa |
? + NADP+ |
- |
? |
1.1.1.2 | (2E)-4-hydroxynon-2-enal + NADPH |
30% of activity with cinnamaldehyde |
Saccharomyces cerevisiae |
(2E)-non-2-ene-1,4-diol + NADP+ |
- |
r |
1.1.1.2 | (2E)-hex-2-enal + NADPH + H+ |
- |
Pelophylax perezi |
(2E)-2-hexen-1-ol + NADP+ |
- |
r |
1.1.1.2 | (2E,4E)-hexa-2,4-dienal + NAD(P)H + H+ |
- |
Mus musculus |
(2E,4E)-6-hydroxyhexa-2,4-dienal + NAD(P)+ |
- |
? |
1.1.1.2 | (2R,3R)-2,3-butanediol + NADP+ |
the enzyme shows higher oxidation activities on the (2R,3R)-(-)-2,3-butanediol and meso-2,3-butanediol than on the (2S,3S)-(+)-2,3-butanediol, indicating that the enzyme predominantly oxidizes the R-hydroxyl group of 2,3-butanediol and minorly functions on the S-hydroxyl group. When meso-2,3-butanediol is oxidized, (S)-2-acetoin is the predominant product, with an enantiomeric excess (ee) of 88%, while oxidation of (2R,3R)-2,3-butanediol results in the production of (R)-2-acetoin with higher stereoselectivity (94% ee) |
Thermococcus guaymasensis |
(R)-2-acetoin + NADPH + H+ |
- |
r |
1.1.1.2 | (2S)-methyl-1-butanol + NADP+ |
39% activity compared to cinnamyl alcohol |
Saccharomyces cerevisiae |
(2S)-methylbutanal + NADPH |
- |
r |
1.1.1.2 | (2S,3S)-2,3-butanediol + NADP+ |
the enzyme shows higher oxidation activities on the (2R,3R)-(-)-2,3-butanediol and meso-2,3-butanediol than on the (2S,3S)-(+)-2,3-butanediol, indicating that the enzyme predominantly oxidizes the R-hydroxyl group of 2,3-butanediol and minorly functions on the S-hydroxyl group. When meso-2,3-butanediol is oxidized, (S)-2-acetoin is the predominant product, with an enantiomeric excess (ee) of 88%, while oxidation of meso-2,3-butanediol results in the production of (R)-2-acetoin with higher stereoselectivity (94% ee) |
Thermococcus guaymasensis |
(S)-2-acetoin + NADPH + H+ |
- |
r |
1.1.1.2 | (4-hydroxy-3-[3-methyl-3-butene-1-ynyl]benzaldehyde) + NADPH + H+ |
eutypine, a toxin produced by Eutypa lata, the causal agent of Eutypa dieback in the grapevine Vitis vinifera |
Vigna radiata |
(4-hydroxy-3-[3-methyl-3-butene-1-ynyl]benzyl alcohol) + NADP+ |
eutypinol, non-toxic metabolite |
ir |