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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.1.1.218
1-indanol + NADP+
-
Oryctolagus cuniculus
1-indanone + NADPH
-
?
1.1.1.218
3-hydroxyhexobarbital + NADP+
does not serve as a substrate for guinea pig enzyme
Oryctolagus cuniculus
?
-
?
1.1.1.218
benzenedihydrodiol + NADP+
-
Oryctolagus cuniculus
?
-
?
1.1.1.218
codeine + NAD(P)+
-
Pseudomonas putida
codeinone + NAD(P)H
-
?
1.1.1.218
codeine + NAD(P)+
oxidation at 120% the rate of morphine oxidation
Pseudomonas putida
codeinone + NAD(P)H
at pH 6.5, + NADPH, reduction of codeinone to codeine
r
1.1.1.218
codeine + NAD(P)+
codeine best substrate
Oryctolagus cuniculus
codeinone + NAD(P)H
-
?
1.1.1.218
codeine + NAD(P)+
non-Theorell-Chance sequential ordered mechanism for codeine oxidation at pH 9.5
Pseudomonas putida
codeinone + NAD(P)H
morphine dehydrogenase follows a Theorell-Chance mechanism for codeinone reduction at pH 7.0
?
1.1.1.218
codeine + NAD(P)+
only weak enzyme activity for codeine
Mesocricetus auratus
codeinone + NAD(P)H
-
?
1.1.1.218
codeine + NAD(P)+
oxidation at 80% the rate of morphine oxidation
Cavia porcellus
codeinone + NAD(P)H
-
?
1.1.1.218
codeine + NAD(P)+
-
Pseudomonas putida M10
codeinone + NAD(P)H
-
?
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