Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 6 of 6
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51more ALKBH1 prefers bubbled or bulged DNAs as substrate. The middle N6-mA in the 3-nt bulge is efficiently demethylated compared to that in the 3-nt bubble (97% vs. 18% demethylation fraction) and the 1st and 3rd N6-mAs are more resistant to demethylation. N6-mAs deposited in the flexible region of hairpin (DNA stem loop), D-loop and R-loop are efficiently demethylated as in bubble and bulge, while those in cruciform and replication fork are less demethylated. m6rA in RNA hairpin, RNA-RNA bubble and RNA-DNA hybrid bubble can also be demethylated by ALKBH1, as well as 5-methylcytosine at anticodon loop and 1-methyladenosine Mus musculus ? - -
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51N6-methyladenine in DNA + 2-oxoglutarate + O2 - Drosophila melanogaster adenine in DNA + formaldehyde + succinate + CO2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51N6-methyladenine in DNA + 2-oxoglutarate + O2 - Homo sapiens adenine in DNA + formaldehyde + succinate + CO2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51N6-methyladenine in DNA + 2-oxoglutarate + O2 - Caenorhabditis elegans adenine in DNA + formaldehyde + succinate + CO2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51N6-methyladenine in DNA + 2-oxoglutarate + O2 - Mus musculus adenine in DNA + formaldehyde + succinate + CO2 - ?
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51N6-methyladenine in DNA + 2-oxoglutarate + O2 the enzyme catalyses oxidative demethylation of DNA N6-methyladenine, a prevalent modification in LINE-1 transposons Mus musculus adenine in DNA + formaldehyde + succinate + CO2 - ?
Results 1 - 6 of 6