EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Eschscholzia californica |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Papaver somniferum |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Coptis chinensis |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
- |
Nelumbo nucifera |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
absolute requirement for an N-methyl group, a 4'-hydroxyl moiety and S-configuration at carbon atom 1 |
Eschscholzia californica |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
one of the key enzymes in biosynthesis of benzylisoquinoline alkaloids in the opium poppy, CYP80B1 catalyzes the second to last step in the formation of (S)-reticuline, the last common intermediate in sanguinarine and morphine biosynthesis, overview |
Papaver somniferum |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
the catalyzes step 5 in the unique, cell type-specific biosynthesis of benzylisoquinoline alkaloids in the opium poppy, biosynthetic pathway leading from L-DOPA to morphine, overview |
Papaver somniferum |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
specific for the substrate |
Papaver somniferum |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme catalyzes a key regulation step in morphine biosynthesis |
Papaver somniferum |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |
1.14.14.102 | (S)-N-methylcoclaurine + [reduced NADPH-hemoprotein reductase] + O2 |
the enzyme is involved in the sanguinarine biosynthetic pathway, overview |
Eschscholzia californica |
(S)-3'-hydroxy-N-methylcoclaurine + [oxidized NADPH-hemoprotein reductase] + H2O |
- |
? |