EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    1.5.3.16 | 1,16-diamino-4,8,13-triazahexadecane + O2 + H2O |
increased activity compared to spermine |
Homo sapiens |
? |
- |
? |
| 1.5.3.16 | 1,16-diamino-4,8,13-triazahexadecane pentahydrochloride + O2 + H2O |
- |
Homo sapiens |
? |
- |
? |
| 1.5.3.16 | alpha-methylspermine + O2 + H2O |
- |
Homo sapiens |
? |
- |
? |
| 1.5.3.16 | benzylamidine + O2 + H2O |
- |
Ascaris suum |
? |
- |
? |
| 1.5.3.16 | more |
no activity with spermidine |
Arabidopsis thaliana |
? |
- |
? |
| 1.5.3.16 | more |
no oxidation activity with spermidine |
Arabidopsis thaliana |
? |
- |
? |
| 1.5.3.16 | more |
AtPAO4 deficiency induces alterations in the expression of genes related to the drought stress response and flavonoid biosynthesis |
Arabidopsis thaliana |
? |
- |
? |
| 1.5.3.16 | more |
in mammalian cells, polyamine catabolism seems to be mediated by the activity of two enzymes, PAO and SMO |
Mus musculus |
? |
- |
? |
| 1.5.3.16 | more |
PAOh1 is upregulated in response to polyamine analogue exposure. N1,N11-bis(ethyl)norspermine results in 5fold induction of PAO mRNA and a more than 3-fold induction of PAO activity |
Homo sapiens |
? |
- |
? |
| 1.5.3.16 | more |
spermine oxidase activity is a direct oxidative stress inducer of DNA damage, thus rendering cells more sensitive to radiation and apoptosis |
Mus musculus |
? |
- |
? |
