   1.14.17.3 | alpha-AE, bifunctional PAM, bifunctional peptidylglycine alpha-amidating monooxygenase, CG3832, hPHMcc, PAM, PAM-1, PAM-2, PAM-A, PAM-B, PAM/PHM, peptide alpha-amidating enzyme, peptide alpha-amide synthase, peptide-alpha-amide synthetase, peptidyl alpha-amidating enzyme, peptidyl alpha-hydroxylating monooxygenase, peptidyl-glycine alpha-amidating monooxygenase, peptidylglycine 2-hydroxylase, peptidylglycine alpha-amidating mono-oxygenase, peptidylglycine alpha-amidating monooxygenase, peptidylglycine alpha-hydroxylase, peptidylglycine alpha-hydroxylating monooxygenase, peptidylglycine alpha-hydroxylating-monooxygenase, peptidylglycine alpha-monooxygenase, peptidylglycine monooxygenase, peptidylglycine-alpha-amidating monooxygenase, PHM, PHMcc, synthase, peptide alpha-amide, type A PAM |
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-, 438565, 438589, 648703, 657649, 657678, 657976, 658004, 658458, 658685, 658976, 658981, 659847, 659916, 660417, 672059, 672113, 673155, 673624, 674179, 674660, 674739, 675602, 676299, 676976, 687277, 696707, 697630, 698481, 698532, 699036, 700421, 715268, 716946, 720977, 726958, 727016, 727146, 727671, 728178, 728237, 728274, 728832, 744315, 744349, 744361, 745055, 745068, 745296, 745298, 745327, 745332, 745459, 746370 |
| 1.14.17.3 | More |
EC 1.14.17.3 is often called peptidylglycine alpha-amidating monooxygenase (PAM) and the alpha-amidated product is mentioned as the product of the reaction, but the alpha-amidation of glycine-extended peptides is a two-step process catalyzed by 2 enzymes: 1. EC 1.14.17.3: production of peptidyl(2-hydroxyglycine) by a copper, molecular oxygen and ascorbate-dependent peptidyl-glycine alpha-hydroxylating monooxygenase (PHM), 2. conversion of the peptidyl-alpha-hydroxyglycine derivative into an alpha-amidated product at physiological pH by peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PHL) |
438567, 438569, 438580, 438583, 438584, 438585, 438587, 438588, 438589, 438590, 438592 |
