0.1
-
(S)-nicotine
wild-type, pH 7.4, 22°C
0.26
-
(S)-6-hydroxynicotine
pH 7.0, 25°C, mutant enzyme K287M
1.14
-
(S)-nicotine
mutant R274A/Y311W/C417W, pH 7.4, 37°C
1.44
-
(S)-nicotine
mutant Y311W, pH 7.4, 22°C
2.03
-
(S)-nicotine
pH 7.0, 40°C
2.5
-
(S)-6-hydroxynicotine
mutant R274A/Y311W/C417W, pH 7.4, 22°C
2.5
-
(S)-6-hydroxynornicotine
pH 7.0, 25°C, mutant enzyme N166A
2.65
-
(S)-nicotine
mutant R274A/Y311W/C417W, pH 7.4, 22°C
4.8
-
(S)-6-hydroxynicotine
pH 7.0, 25°C, mutant enzyme N166A
7.3
-
(S)-6-hydroxynicotine
pH 7.0, 40°C