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EC Number	pH Minimum	pH Maximum	Commentary	Reference
1.5.1.33	4	8	the enzyme has a pH profile somewhat broader than that of other pteridine reductases and exhibits about 20% of maximal activity at pH 8.0, inactive at pH 10.0, maximal activity at pH 6.0	765008
1.5.1.33	4	9	-	725417
1.5.1.33	4.5	7	pH 4.5: about 50% of maximal activity, pH 7.0: about 30% of maximal activity with biopterin	484956
1.5.1.33	4.7	7	significant decline of activity at pH 7 and 4.7	484951

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Release 2023.1 (January 2023)