EC Number |
Cofactor |
Reference |
---|
1.1.1.23 | NAD+ |
- |
286322, 286323, 286324, 286325, 286326, 286327, 286328, 286329, 286330, 286331, 286332, 286333, 286334, 286335, 286336, 286337, 286338, 286339, 286340, 723090, 723322, 740116, 740147, 741402, 741455 |
1.1.1.23 | NAD+ |
amino acid residues contributing to NAD+ binding include Tyr129, Gly132, and Asn221 for phosphate binding, Gln193 and Asn221 for adenosine sugar binding, and Phe58, Gln193, and Tyr223 for adenine base binding |
721426 |
1.1.1.23 | NAD+ |
binding site structure |
657194 |
1.1.1.23 | NAD+ |
the amine group is responsible of the substrate orientation by interacting with the Zn2+ while the overall stabilization of the cation changed between the unbound and bound forms |
741455 |
1.1.1.23 | NAD+ |
the amine group is responsible of the substrate orientation by interacting with the Zn2+ while the overall stabilization of the cation changes between the unbound and bound forms |
741455 |