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EC Number Cofactor Commentary Reference
Display the reaction diagram Show all sequences 1.1.1.292NADH wild-type enzyme and mutant enzymes S10G, S33D, K94G, D176A, H180A and G206I shows no activity with NADH. Mutant enzymes A13G, S10G/A13G and S33D/A13G are active with NADH 667698
Display the reaction diagram Show all sequences 1.1.1.292NADP+ - 667264, 762866
Display the reaction diagram Show all sequences 1.1.1.292NADPH - 762866
Display the reaction diagram Show all sequences 1.1.1.292NADPH inactive towards NADH 667264
Display the reaction diagram Show all sequences 1.1.1.292NADPH the N-terminal domain displays a Rossman fold and contains the cofactor binding site. The intact crystals contain the oxidized cofactor NADP+ 667698
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