EC Number   |
Cofactor |
Reference |
|---|
    4.1.1.19 | more |
pyruvoyl-dependent decarboxylase, synthesised as zymogen. The pyruvoyl cofactor results from the self-modification of an internal serine (Ser44) residue of the proenzyme, the pyruvoyl group functions through the formation of a Schiff base with the substrate to promote decarboxylation |
719521 |
| 4.1.1.19 | more |
the enzyme contains a reactive pyruvoyl group |
656053 |
| 4.1.1.19 | more |
the enzyme contains a reactive pyruvoyl group, the proenzyme undergoes autocatalytic serinolysis, resulting in the formation of two chains and the creation of a pyruvoyl group, which is the cofactor for the decarboxylation reaction |
690235 |
| 4.1.1.19 | more |
the pyruvoyl group of the enzyme is generated by an autocatalytic internal serinolysis reaction at Ser53 in the proenzyme resulting in two polypeptide chains |
657363 |
| 4.1.1.19 | more |
The serine residue at N terminus of the {alpha} subunit forms a reactive pyruvoyl group that functions analogously to pyridoxal 5'-phosphate |
680506 |
| 4.1.1.19 | pyridoxal 5'-phosphate |
- |
667042, 677506, 681117, 681120, 681122, 681527, 681617, 682296, 682406, 685687, 690809, 693862, 694355, 694642, 701516, 702296, 705633, 705931, 706253, 706283, 706859, 713633, 715526, 715563, 716201, 716715, 746728, 746986, 747924, 748115, 748321, 748897, 749002, 749140 |
| 4.1.1.19 | pyridoxal 5'-phosphate |
0.8 mM, stimulates by about 30% |
4080 |
| 4.1.1.19 | pyridoxal 5'-phosphate |
a fold III, pyridoxal 5'-phosphate-dependent enzyme |
678266 |
| 4.1.1.19 | pyridoxal 5'-phosphate |
a formyl group of pyridoxal 5'-phosphate is bound to the 6-amino group of a Lys residue. Binds 10 mol of pyridoxal 5'-phosphate per mol of enzyme |
4086 |
| 4.1.1.19 | pyridoxal 5'-phosphate |
absolute requirement |
655193 |
