EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
|---|
    2.5.1.19 | -999 |
- |
glyphosate |
any substitutions for residue Pro101 decrease glyphosate binding affinity and inhibitor potency |
693010 |
| 2.5.1.19 | -999 |
- |
glyphosate |
KI/KM (phosphoenolpyruvate): 0.01 |
694557 |
| 2.5.1.19 | -999 |
- |
glyphosate |
Ki/KM (phosphoenolpyruvate): 0.36, reconstituted G2-EPSPS (by intein-mediated protein complementation), crude lysate from overexpressing Escherichia coli ER2799, malachite green dye assay |
690523 |
| 2.5.1.19 | -999 |
- |
glyphosate |
Ki/KM (phosphoenolpyruvate): 0.52, full-length G2 EPSPS, crude lysate from overexpressing Escherichia coli ER2799, malachite green dye assay |
690523 |
| 2.5.1.19 | -999 |
- |
glyphosate |
KI/KM (phosphoenolpyruvate): 14 |
694557 |
| 2.5.1.19 | -999 |
- |
more |
- |
658112, 658759 |
| 2.5.1.19 | 0.0000039 |
- |
(3R,4S,5R)-4-hydroxy-5-[(2R)-1-hydroxy-1-oxo-2-phosphono-propan-2-yl]oxy-3-phosphonooxy-cyclohexene-1-carboxylic acid |
+/-0.6 nM |
690885 |
| 2.5.1.19 | 0.0000078 |
- |
(3R,4S,5R)-5-[(2R)-1,1-difluoro-3-hydroxy-3-oxo-2-phosphonooxy-propan-2-yl]oxy-4-hydroxy-3-phosphonooxy-cyclohexene-1-carboxylic acid |
+/-0.5 nM |
690885 |
| 2.5.1.19 | 0.000015 |
- |
shikimate 3-phosphate-5-carboxymethyl-(2R)-phosphonate |
vs. 5-enolpyruvylshikimate-3-phosphate |
638186 |
| 2.5.1.19 | 0.000016 |
- |
(3R,4S,5R)-5-((R)-1-carboxy-1-phosphono-ethoxy)-4-hydroxy-3-phosphonooxy-cyclohex-1-enecarboxylic acid |
versus 3-phosphoshikimate |
658112 |
