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EC Number Crystallization (Commentary)
Display the reaction diagram Show all sequences crystal structures of chromopyrrolic acid-bound and chromopyrrolic acid-free forms of enzyme component StaP. The enzyme attains a more ordered conformation upon binding of the substrate. Substantial conformational changes are observed at and around the substrate-binding pocket to optimize interactions with the enzyme. The enzyme–chromopyrrolic acid complex structure reveals that chromopyrrolic acid has a twisted-butterfly shape in the active site, which is perpendicular to the heme plane
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