EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    2.5.1.7 | -999 |
- |
more |
in wild-type background, IC50 of fosfomycin is 2,048 microg/ml. In a strain with antisense-based expression attenuation of the MurA1 gene encoding UDP-N-acetylglucosamine enolpyruvyl transferase, IC50 value is 126 microg/ml. Prsence of xylose further decreases the IC50 value to 18 microg/ml |
684494 |
| 2.5.1.7 | 0.000053 |
- |
6-chloro-7-(4-methoxyphenoxy)quinoline-5,8-dione |
pH and temperature not specified in the publication |
738855 |
| 2.5.1.7 | 0.000064 |
- |
7-chloro-6-(4-hydroxyphenoxy)quinoline-5,8-dione |
pH and temperature not specified in the publication |
738855 |
| 2.5.1.7 | 0.0001 |
- |
ebselen |
50 mM Tris-HCl, pH 7.8, compound displays an anti-MurA activity that is above 90% at a concentration below 0.002 mM |
705091 |
| 2.5.1.7 | 0.0002 |
- |
RWJ-3981 |
pH and temperature not specified in the publication |
737812 |
| 2.5.1.7 | 0.00025 |
- |
2-oxo-1,3-benzoxathiol-6-yl sulfamate |
in 50 mM Tris-HCl, pH 7.9, at 37°C |
722469 |
| 2.5.1.7 | 0.00028 |
- |
4,7-dichloro-5-hydroxy-1,3-benzoxathiol-2-one |
in 50 mM Tris-HCl, pH 7.9, at 37°C |
722469 |
| 2.5.1.7 | 0.00028 |
- |
4,7-dichloro-5-hydroxy-1,3-benzoxathiol-2-one |
pH and temperature not specified in the publication |
737812 |
| 2.5.1.7 | 0.0004 |
- |
thimerosal |
50 mM Tris-HCl, pH 7.8, compound displays an anti-MurA activity that is above 90% at a concentration below 0.002 mM |
705091 |
| 2.5.1.7 | 0.00046 |
- |
2-oxo-1,3-benzoxathiol-5-yl methylcarbamate |
in 50 mM Tris-HCl, pH 7.9, at 37°C |
722469 |
