EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.5.1.29 | Carcinoma, Hepatocellular |
24716791 |
GGPPS1 predicts the biological character of hepatocellular carcinoma in patients with cirrhosis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
4
1 |
| 2.5.1.29 | Cholestasis |
31905247 |
Conditional loss of geranylgeranyl diphosphate synthase alleviates acute obstructive cholestatic liver injury by regulating hepatic bile acid metabolism. |
causal interaction
ongoing research
unassigned |
1
1
0 |
| 2.5.1.29 | Dystocia |
33340314 |
Ggps1 deficiency in the uterus results in dystocia by disrupting uterine contraction. |
causal interaction
unassigned |
4
0 |
| 2.5.1.29 | Fatty Liver |
29971772 |
Geranylgeranyl diphosphate synthase (GGPPS) regulates non-alcoholic fatty liver disease (NAFLD)-fibrosis progression by determining hepatic glucose/fatty acid preference under high-fat diet conditions. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
2
3
1
0 |
| 2.5.1.29 | geranylgeranyl diphosphate synthase deficiency |
31120854 |
Geranylgeranyl diphosphate synthase deficiency aggravates lung fibrosis in mice by modulating TGF-?1/BMP-4 signaling. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 2.5.1.29 | geranylgeranyl diphosphate synthase deficiency |
33340314 |
Ggps1 deficiency in the uterus results in dystocia by disrupting uterine contraction. |
causal interaction
unassigned |
4
0 |
| 2.5.1.29 | geranylgeranyl diphosphate synthase deficiency |
33729030 |
Geranylgeranyl diphosphate synthase deficiency hyperactivates macrophages and aggravates lipopolysaccharide-induced acute lung injury. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.5.1.29 | Hearing Loss |
32403198 |
GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome. |
causal interaction
unassigned |
1
0 |
| 2.5.1.29 | Hyperinsulinism |
24716791 |
GGPPS1 predicts the biological character of hepatocellular carcinoma in patients with cirrhosis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
4
4
1 |
| 2.5.1.29 | Infections |
16664817 |
Biosynthesis of the Macrocyclic Diterpene Casbene in Castor Bean (Ricinus communis L.) Seedlings : Changes in Enzyme Levels Induced by Fungal Infection and Intracellular Localization of the Pathway. |
causal interaction
unassigned |
1
0 |
