EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
1.10.5.1 | Agranulocytosis |
27168101 |
Genetic risk factors for clozapine-induced neutropenia and agranulocytosis in a Dutch psychiatric population. |
diagnostic usage unassigned |
1 0 |
1.10.5.1 | Alzheimer Disease |
21803122 |
Increased hippocampal quinone reductase 2 in Alzheimer's disease. |
causal interaction unassigned |
2 0 |
1.10.5.1 | Alzheimer Disease |
26609153 |
Expression of Quinone Reductase-2 in the Cortex Is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint. |
causal interaction unassigned |
1 0 |
1.10.5.1 | Amnesia |
20861374 |
Loss of quinone reductase 2 function selectively facilitates learning behaviors. |
ongoing research unassigned |
4 0 |
1.10.5.1 | Breast Neoplasms |
19351655 |
Functional Polymorphisms, Altered Gene Expression and Genetic Association Link NRH:Quinone Oxidoreductase 2 to Breast Cancer with Wild-type p53. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 3 2 1 |
1.10.5.1 | Breast Neoplasms |
20558190 |
Synthesis of carbon-11-labeled casimiroin analogues as new potential PET agents for imaging of quinone reductase 2 and aromatase expression in breast cancer. |
causal interaction diagnostic usage therapeutic application unassigned |
2 3 4 0 |
1.10.5.1 | Breast Neoplasms |
33777113 |
Association Between a Tri-allelic Polymorphism in the Estrogen Metabolism Oxidoreductase NRH:Quinone Oxidoreductase 2 Gene and Risk of Breast Cancer by Molecular Subtype. |
causal interaction diagnostic usage ongoing research unassigned |
1 1 1 0 |
1.10.5.1 | Carcinogenesis |
15342368 |
Deficiency of NRH:quinone oxidoreductase 2 increases susceptibility to 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene-induced skin carcinogenesis. |
causal interaction unassigned |
3 0 |
1.10.5.1 | Carcinogenesis |
16545679 |
Nuclear factor Nrf2 and antioxidant response element regulate NRH:quinone oxidoreductase 2 (NQO2) gene expression and antioxidant induction. |
causal interaction therapeutic application unassigned |
1 1 0 |
1.10.5.1 | Carcinogenesis |
22770696 |
Null association of NQO1 609C>T and NQO2 -3423G>A polymorphisms with susceptibility and prognosis of Esophageal cancer in north Indian population and meta-analysis. |
causal interaction therapeutic application unassigned |
3 1 0 |