EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.11.66 | Adenocarcinoma |
24481461 |
Stimulation of ?-catenin and colon cancer cell growth by the KDM4B histone demethylase. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
2
0 |
| 1.14.11.66 | Adenocarcinoma |
26166558 |
Overexpression of Lysine-Specific Demethylase 1 Is Associated With Tumor Progression and Unfavorable Prognosis in Chinese Patients With Endometrioid Endometrial Adenocarcinoma. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
1
0 |
| 1.14.11.66 | Adenocarcinoma |
30556125 |
Loss of KDM6A characterizes a poor prognostic subtype of human pancreatic cancer and potentiates HDAC inhibitor lethality. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
4
1
2 |
| 1.14.11.66 | Adenocarcinoma |
31442435 |
The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
4
4
0 |
| 1.14.11.66 | Adenocarcinoma |
32403054 |
Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4. |
diagnostic usage
unassigned |
3
0 |
| 1.14.11.66 | Adenocarcinoma of Lung |
27630338 |
The Prognostic Impact of Jumonji Domain-containing 2B in Patients with Resected Lung Adenocarcinoma. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
2
3
0 |
| 1.14.11.66 | Adenocarcinoma of Lung |
28521455 |
KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
1
1
0 |
| 1.14.11.66 | Adenocarcinoma of Lung |
30760542 |
LSD1 inhibition attenuates tumor growth by disrupting PLK1 mitotic pathway. |
causal interaction
unassigned |
4
0 |
| 1.14.11.66 | Adenocarcinoma of Lung |
34270886 |
Histone demethylase KDM5A enhances cell proliferation, induces EMT in lung adenocarcinoma cells, and have a strong causal association with paclitaxel resistance. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
2
2
4 |
| 1.14.11.66 | Alzheimer Disease |
33139560 |
The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration. |
unassigned |
0 |
