EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   1.14.14.80 | Ascorbic Acid Deficiency |
9055344 |
Ascorbic acid deficiency decreases the expression of CYP4A1 in liver microsomes of guinea pigs. |
ongoing research
unassigned |
1
0 |
| 1.14.14.80 | Carcinoma, Hepatocellular |
2766933 |
The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes. |
ongoing research
unassigned |
4
0 |
| 1.14.14.80 | Carcinoma, Hepatocellular |
10428978 |
Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha. |
ongoing research
unassigned |
3
0 |
| 1.14.14.80 | Carcinoma, Hepatocellular |
30069903 |
Cytochrome P450 4A11 expression in tumor cells: A favorable prognostic factor for hepatocellular carcinoma patients. |
causal interaction
diagnostic usage
ongoing research
unassigned |
1
4
2
0 |
| 1.14.14.80 | Cardiotoxicity |
22867862 |
Chronic Doxorubicin Cardiotoxicity Modulates Cardiac Cytochrome P450-Mediated Arachidonic Acid Metabolism in Rats. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
1
4
2 |
| 1.14.14.80 | Endotoxemia |
22975359 |
NS-398 reverses hypotension in endotoxemic rats: Contribution of eicosanoids, NO, and peroxynitrite. |
causal interaction
unassigned |
3
0 |
| 1.14.14.80 | Fatty Liver |
24481563 |
Effects of binge ethanol on lipid homeostasis and oxidative stress in a rat model of nonalcoholic fatty liver disease. |
unassigned |
0 |
| 1.14.14.80 | Fatty Liver, Alcoholic |
17510198 |
Undernutrition enhances alcohol-induced hepatocyte proliferation in the liver of rats fed via total enteral nutrition. |
causal interaction
diagnostic usage
unassigned |
1
1
0 |
| 1.14.14.80 | Glioma |
18591218 |
Expression of CYP4A1 in U251 human glioma cell induces hyperproliferative phenotype in vitro and rapidly growing tumors in vivo. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 1.14.14.80 | Hepatomegaly |
20614104 |
Hepatocellular hypertrophy and cell proliferation in Sprague-Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPAR? and CAR/PXR. |
causal interaction
unassigned |
3
0 |
