EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.2.1.8 | Infections |
16426571 |
Disulfiram irreversibly aggregates betaine aldehyde dehydrogenase--a potential target for antimicrobial agents against Pseudomonas aeruginosa. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
1
1
0 |
| 1.2.1.8 | Infections |
20933050 |
The disulfiram metabolites S-methyl-N,N-diethyldithiocarbamoyl sulfoxide and S-methyl-N,N-diethylthiocarbamoyl sulfone irreversibly inactivate betaine aldehyde dehydrogenase from Pseudomonas aeruginosa, both in vitro and in situ, and arrest bacterial growth. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 1.2.1.8 | Starvation |
10628850 |
Upregulation of stress response genes and ABC transporters in anaerobic stationary-phase Mycobacterium smegmatis. |
unassigned |
0 |
| 1.2.1.8 | Tuberculosis |
10628850 |
Upregulation of stress response genes and ABC transporters in anaerobic stationary-phase Mycobacterium smegmatis. |
unassigned |
0 |
