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EC Number
Protein Variants
Commentary
Reference
1.1.1.179
A36D
site-directed mutagenesis
684150
1.1.1.179
D280A
by site-directed mutagenesis
684150
1.1.1.179
F154A
by site-directed mutagenesis
684150
1.1.1.179
F279A
by site-directed mutagenesis
684150
1.1.1.179
H76Q
by site-directed mutagenesis
684150
1.1.1.179
H79Q
by site-directed mutagenesis
684150
1.1.1.179
H79Q
increase in Km more than 25fold, increase in Kd more than 7fold, with high ionic strength Km increased by 190fold and inhibited the enzyme
286127
1.1.1.179
H79Q
large increase in Km for coenzyme and substrates
286128
1.1.1.179
K97M
by site-directed mutagenesis
684150
1.1.1.179
K97R
by site-directed mutagenesis
684150
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