EC Number   |
Protein Variants |
Reference  |
|---|
  1.13.11.48 | H251A |
2258fold lower specific activity than wild-type |
-, 658042 |
| 1.13.11.48 | C69S |
site-directed mutagenesis, the mutant has catalytic properties that are identical to those of wild-type HOD |
-, 673207, 684175 |
| 1.13.11.48 | C69S |
stable in its monomeric form |
-, 673207 |
| 1.13.11.48 | E224A |
decreased Km for O2 |
-, 673207 |
| 1.13.11.48 | E224A/C69S |
site-directed mutagenesis, mutant apparent kinetic parameters compared to the wild-type enzyme |
673207 |
| 1.13.11.48 | F219Y |
does not affect the kinetic parameters of the enzyme |
673207 |
| 1.13.11.48 | F219Y/C69S |
site-directed mutagenesis, mutant apparent kinetic parameters compared to the wild-type enzyme |
673207 |
| 1.13.11.48 | H102Q |
Km for the heteroaromatic substrate is increased only 2.8fold, and kcat is reduced 2.3fold |
-, 673207 |
| 1.13.11.48 | H102Q/C69S |
site-directed mutagenesis, mutant apparent kinetic parameters compared to the wild-type enzyme |
673207 |
| 1.13.11.48 | S101A |
about 21fold increase in the Km for the organic substrate |
-, 673207 |
