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Results 1 - 10 of 13 > >>
EC Number Protein Variants Commentary Reference
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5H156A the mutant shows less than 10% of wild type activity 751026
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5H156C the mutant shows less than 10% of wild type activity 751026
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5M149A mutation alters the heme coordination, which becomes a 6-coordinate low spin species with the amide nitrogen atom of the Q187 residue bound to the heme iron. In the mutant, two CO conformers are present corresponding to open (A0) and closed (A1) conformations. Residue M149 is involved in the formation of a covalent bond with a vinyl substituent of heme b at excess of hydrogen peroxide -, 752779
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5M149A/Q187A binding of coproheme is significantly decreased. In the absence of the Q187, only the A0 conformer is found -, 752779
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5Q187A in the absence of the Q187, only the A0 conformer is found compared to two CO conformers are present corresponding to open (A0) and closed (A1) conformations in mutant M149A -, 752779
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5K151A disruption of the H-bond interactions with p2 and p4, impairs the structural rearrangement upon binding of coproheme. Decarboxylation activity is highly impaired -, 754346
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5Q187A catalytic activity similar to wild-type 754346
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5R133A catalytic activity similar to wild-type -, 754346
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5R179A catalytic activity similar to wild-type -, 754346
Show all pathways known for 1.3.98.5Display the word mapDisplay the reaction diagram Show all sequences 1.3.98.5Y113A catalytic activity similar to wild-type -, 754346
Results 1 - 10 of 13 > >>