Refine search

Search Engineering

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 114 > >>
EC Number
Amino acid exchange
Commentary
Reference
A246C
reverse activity stronger affected than cyclic activity
A253C
reverse activity stronger affected than cyclic activity
A348C
mutation introduced into a cysteine-free mutant enzyme, mutant shows markedly reduced activity
A390C
mutation introduced into a cysteine-free mutant enzyme
A398C
the mutant with wild type activity shows increased ratios between the rates of the forward and reverse reactions, thus approaching that of the wild type enzyme
A432C
mutation in domain III, reverse reaction in the presence of domain I from R. rubrum, 150% higher reaction rate than wild-type domain III/R. rubrum domain I mixture
A432C
the mutant shows increased ratios between the rates of the forward and reverse reactions, thus approaching that of the wild type enzyme
C292T/C339T/C395S/C397T/C435S
cysteine of the alpha subunits replaced, similar activity as wild-type
C292T/C339T/C395S/C397T/C435S/C147S/C260S
all 7 cysteines of the enzyme, 5 localized in the alpha subunit and 2 in the beta subunit, are replaced, the cysteine-free mutant shows about 5fold more activity in the reduction of acetylpyridine adenine dinucleotide by NADH than wild-type, the cyclic reduction of acetylpyridine adenine dinucleotide by NADH via NADPH is 2-2.5fold more activ
D135N
mutation has no effect in binding affinity of either NAD+ or NADH; the mutant shows reduced activity compared to the wild type enzyme
Results 1 - 10 of 114 > >>