EC Number   |
Protein Variants |
Reference  |
|---|
   7.1.1.1 | C292T/C339T/C395S/C397T/C435S |
cysteine of the alpha subunits replaced, similar activity as wild-type |
392662 |
| 7.1.1.1 | C292T/C339T/C395S/C397T/C435S/C147S/C260S |
all 7 cysteines of the enzyme, 5 localized in the alpha subunit and 2 in the beta subunit, are replaced, the cysteine-free mutant shows about 5fold more activity in the reduction of acetylpyridine adenine dinucleotide by NADH than wild-type, the cyclic reduction of acetylpyridine adenine dinucleotide by NADH via NADPH is 2-2.5fold more activ |
392662 |
| 7.1.1.1 | A348C |
mutation introduced into a cysteine-free mutant enzyme, mutant shows markedly reduced activity |
392663 |
| 7.1.1.1 | A390C |
mutation introduced into a cysteine-free mutant enzyme |
392663 |
| 7.1.1.1 | K424C |
mutation introduced into a cysteine-free mutant enzyme, mutant shows markedly reduced activity |
392663 |
| 7.1.1.1 | R425C |
mutation introduced into a cysteine-free mutant enzyme, mutant shows markedly reduced activity |
392663 |
| 7.1.1.1 | D401E |
mutation in beta subunit |
392664 |
| 7.1.1.1 | D401G |
mutation in beta subunit |
392664 |
| 7.1.1.1 | D401V |
mutation in beta subunit |
392664 |
| 7.1.1.1 | E413D |
mutation in beta subunit |
392664 |
