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EC Number Protein Variants Commentary Reference
Show all pathways known for 1.1.1.245Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.245N249Y mutant N249Y displays non-cooperative behavious in coenzyme binding under the same experimental conditions used for the wild-type enzyme (that exhibits linearity of NAD(H) binding at pH 9.8 and at moderate ionic strength, in addition to positive cooperativity at pH 7.8 and 6.8, and at pH 9.8 in the presence of salt. NADH binding is positively cooperative below 20°C and negatively cooperative at 40–50°) 667502
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