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EC Number Protein Variants Commentary Reference
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64A203V inactive enzyme 287223
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64E215D inactive enzyme 287221
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64F208I inactive enzyme 287221
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64M235V inactive enzyme 287223
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64P282L inactive enzyme 287221
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64R80I mutant enzyme shows negligible conversion of androst-4-ene-3,17-dione to testosterone. The Km-value for androstenedione is 80fold higher than the KM-value for the wild-type enzyme 658172
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64R80K conversion of androst-4-ene-3,17-dione to testosterone is reduced as compared to wild-type enzyme. The Km-value for androstenedione is 3.5fold higher than the KM-value for the wild-type enzyme 658172
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64R80L conversion of androst-4-ene-3,17-dione to testosterone is strongly reduced as compared to wild-type enzyme. The Km-value for androstenedione is 21.6fold higher than the KM-value for the wild-type enzyme 658172
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64R80M mutant enzyme shows negligible conversion of androst-4-ene-3,17-dione to testosterone. The Km-value for androstenedione is 90.7fold higher than the KM-value for the wild-type enzyme 658172
Show all pathways known for 1.1.1.64Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.64R80Q - 287223
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