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EC Number
Protein Variants
Commentary
Reference
1.13.11.91
G95C
variant is able to form a cysteine-tyrosine crosslink homologous to that found in mammalian cysteine dioxygenases. Activity of this variant is severely impaired
-
,
758787
1.13.11.91
H157N
over 3fold reduction in kcat/Km value
758826
1.13.11.91
Q62R
variant retains both 3-mercaptopropanoate and cysteine dioxygenase activity
-
,
758823
1.13.11.91
R168A
variant does not fold properly
-
,
758823
1.13.11.91
R168C
variant does not fold properly
-
,
758823
1.13.11.91
Y159F
3fold reduction in kcat/Km value. Fe coordination of cysteine is switched from thiolate only to bidentate (thiolate/amine) for the variant
758826
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