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Results 1 - 10 of 23 > >>
EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51C118A m6A demethylase activity similar to wild-type, about 25% decrease in apurinic/apyrimidinic lyase activity 764135
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51C118A/C129A about 50% decrease in m6A demethylase activity, about 20% decrease in apurinic/apyrimidinic lyase activity 764135
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51C129A about 90% decrease in m6A demethylase activity, about 30% decrease in apurinic/apyrimidinic lyase activity 764135
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51D186A inactive 742235
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51D233A no residual m6A demethylase activity, about 30% decrease in apurinic/apyrimidinic lyase activity 764135
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51D233A reduced activity of the recombinant mutant protein 736883
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51D233A residue plays an important role in substrate recognition and catalysis 764114
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51H113A/C118A/C129A/H134A no residual m6A demethylase activity, about 55% decrease in apurinic/apyrimidinic lyase activity 764135
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51H231A no residual m6A demethylase activity, about 20% decrease in apurinic/apyrimidinic lyase activity 764135
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.51H231A residue plays an important role in substrate recognition and catalysis 764114
Results 1 - 10 of 23 > >>