EC Number |
Protein Variants |
Reference |
---|
1.3.8.12 | A282F |
inactive |
763257 |
1.3.8.12 | A282F |
site-directed mutagenesis, inactive mutant |
763257 |
1.3.8.12 | A282F/F284A |
site-directed mutagenesis, mutant is inactive with succinyl-CoA, but shows residual activity with (S2)-methylsuccinyl-CoA |
763257 |
1.3.8.12 | A282F/F284A |
the double mutant is still able to convert (2S)-methyl-succinyl-CoA, however with less than 0.2% of the relative catalytic efficiency |
763257 |
1.3.8.12 | A282F/F284L |
site-directed mutagenesis, inactive mutant |
763257 |
1.3.8.12 | A282F/F284L |
the double mutant does not show any activity with succinyl-CoA |
763257 |
1.3.8.12 | A282F/F284V |
site-directed mutagenesis, inactive mutant |
763257 |
1.3.8.12 | A282F/F284V |
the double mutant does not show any activity with succinyl-CoA |
763257 |
1.3.8.12 | A282I |
inactive |
763257 |
1.3.8.12 | A282I |
site-directed mutagenesis, inactive mutant |
763257 |