EC Number   |
Protein Variants |
Reference |
|---|
    4.1.1.37 | A22V |
soluble but reduced catalytic activity |
703279 |
| 4.1.1.37 | A80S |
less than 12% of the specific activity of wild-type enzyme, Q38R-glutathione S-transferase fusion protein |
666917 |
| 4.1.1.37 | C705A |
site-directed mutagenesis |
651454 |
| 4.1.1.37 | D306Y |
mutation results in an insoluble recombinant protein |
703118 |
| 4.1.1.37 | D79N |
misfolded protein that is trafficked to inclusion bodies |
703279 |
| 4.1.1.37 | D86 |
site-directed mutagenesis |
650999 |
| 4.1.1.37 | D86E |
site-directed mutagenesis |
650999 |
| 4.1.1.37 | D86G |
site-directed mutagenesis |
650999 |
| 4.1.1.37 | F217Y |
recombinant mutant of the single chain of both modules substrate uroporphyrinogen-I, 2.5% of recombinant wild-type |
705145 |
| 4.1.1.37 | F217Y |
recombinant mutant of the single chain of both modules substrate uroporphyrinogen-III, 14.5% of recombinant wild-type |
705145 |
