EC Number |
Protein Variants |
Reference |
---|
4.4.1.20 | A444C |
the mutation is associated with the risk of ischemic cerebrovascular disease |
690662 |
4.4.1.20 | A52S |
mutation increases the Km-value for the recombinant enzyme for glutathione |
644486, 644499 |
4.4.1.20 | C56S |
mutant enzyme without altered function |
644499 |
4.4.1.20 | C56S |
not inhibited by N-ethylmaleimide |
666794 |
4.4.1.20 | C56S/C82 |
mutant enzyme without altered function |
644499 |
4.4.1.20 | C82V |
mutant enzyme without altered function |
644499 |
4.4.1.20 | E4K |
causes allergic diseases in patients such as bronchial asthma or allergic dermatitis |
665246 |
4.4.1.20 | G1072A |
the mutation is associated with the risk of ischemic cerebrovascular disease |
690662 |
4.4.1.20 | L121M |
by site-directed mutagenesis to prepare the selenomethionine-substituted LTC4S, the mutant yeast clone is grown with selenomethionine, purified and crystallized similarly to the wild-type enzyme |
682093 |
4.4.1.20 | LTCS(1-115) |
C-terminally truncated protein, gives a bioluminescence resonance energy transfer signal when fused to Renilla luciferase |
664161 |