Sequence of ARNA_ECOLI
EC Number:2.1.2.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
UDP-4-amino-4-deoxy-L-arabinose formyltransferase
P77398
Escherichia coli (strain K12)
660
74289
Reaction
10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose
Other sequences found for EC No. 2.1.2.13
General information:
Sequence
0 MKTVVFAYHD MGCLGIEALL AAGYEISAIF THTDNPGEKA FYGSVARLAA ERGIPVYAPD
60 NVNHPLWVER IAQLSPDVIF SFYYRHLIYD EILQLAPAGA FNLHGSLLPK YRGRAPLNWV
120 LVNGETETGV TLHRMVKRAD AGAIVAQLRI AIAPDDIAIT LHHKLCHAAR QLLEQTLPAI
180 KHGNILEIAQ RENEATCFGR RTPDDSFLEW HKPASVLHNM VRAVADPWPG AFSYVGNQKF
240 TVWSSRVHPH ASKAQPGSVI SVAPLLIACG DGALEIVTGQ AGDGITMQGS QLAQTLGLVQ
300 GSRLNSQPAC TARRRTRVLI LGVNGFIGNH LTERLLREDH YEVYGLDIGS DAISRFLNHP
360 HFHFVEGDIS IHSEWIEYHV KKCDVVLPLV AIATPIEYTR NPLRVFELDF EENLRIIRYC
420 VKYRKRIIFP STSEVYGMCS DKYFDEDHSN LIVGPVNKPR WIYSVSKQLL DRVIWAYGEK
480 EGLQFTLFRP FNWMGPRLDN LNAARIGSSR AITQLILNLV EGSPIKLIDG GKQKRCFTDI
540 RDGIEALYRI IENAGNRCDG EIINIGNPEN EASIEELGEM LLASFEKHPL RHHFPPFAGF
600 RVVESSSYYG KGYQDVEHRK PSIRNAHRCL DWEPKIDMQE TIDETLDFFL RTVDLTDKPS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
515913
Breazeale S.D.,Ribeiro A.A.,Raetz C.R.H.
Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose.
J. Biol. Chem.
277
2886-2896
2002
515914
Yamamoto Y.,Aiba H.,Baba T.,Hayashi K.,Inada T.,Isono K.,Itoh T.,Kimura S.,Kitagawa M.,Makino K.,Miki T.,Mitsuhashi N.,Mizobuchi K.,Mori H.,Nakade S.,Nakamura Y.,Nashimoto H.,Oshima T.,Oyama S.,Saito N.,Sampei G.,Satoh Y.,Sivasundaram S.,Tagami H.,Takahashi H.,Takeda J.,Takemoto K.,Uehara K.,Wada C.,Yamagata S.,Horiuchi T.
Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.
DNA Res.
4
91-113
1997
515915
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
515916
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
515917
Winfield M.D.,Groisman E.A.
Phenotypic differences between Salmonella and Escherichia coli resulting from the disparate regulation of homologous genes.
Proc. Natl. Acad. Sci. U.S.A.
101
17162-17167
2004
515918
Breazeale S.D.,Ribeiro A.A.,McClerren A.L.,Raetz C.R.H.
A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-amino-4-deoxy-L-arabinose: identification and function of UDP-4-deoxy-4-formamido-L-arabinose.
J. Biol. Chem.
280
14154-14167
2005
515919
Yan A.,Guan Z.,Raetz C.R.H.
An undecaprenyl phosphate-aminoarabinose flippase required for polymyxin resistance in Escherichia coli.
J. Biol. Chem.
282
36077-36089
2007
515920
Gatzeva-Topalova P.Z.,May A.P.,Sousa M.C.
Crystal structure of Escherichia coli ArnA (PmrI) decarboxylase domain. A key enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance.
Biochemistry
43
13370-13379
2004
515921
Gatzeva-Topalova P.Z.,May A.P.,Sousa M.C.
Crystal structure and mechanism of the Escherichia coli ArnA (PmrI) transformylase domain. An enzyme for lipid A modification with 4-amino-4-deoxy-L-arabinose and polymyxin resistance.
Biochemistry
44
5328-5338
2005
515922
Williams G.J.,Breazeale S.D.,Raetz C.R.H.,Naismith J.H.
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis.
J. Biol. Chem.
280
23000-23008
2005
515923
Gatzeva-Topalova P.Z.,May A.P.,Sousa M.C.
Structure and mechanism of ArnA: conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance.
Structure
13
929-942
2005
