Sequence of METAS_ECOLI
EC Number:2.3.1.46
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine
Other sequences found for EC No. 2.3.1.46
General information:
Sequence
0 MPIRVPDELP AVNFLREENV FVMTTSRASG QEIRPLKVLI LNLMPKKIET ENQFLRLLSN
60 SPLQVDIQLL RIDSRESRNT PAEHLNNFYC NFEDIQDQNF DGLIVTGAPL GLVEFNDVAY
120 WPQIKQVLEW SKDHVTSTLF VCWAVQAALN ILYGIPKQTR TEKLSGVYEH HILHPHALLT
180 RGFDDSFLAP HSRYADFPAA LIRDYTDLEI LAETEEGDAY LFASKDKRIA FVTGHPEYDA
240 QTLAQEFFRD VEAGLDPDVP YNYFPHNDPQ NTPRASWRSH GNLLFTNWLN YYVYQITPYD
300 LRHMNPTLD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
58284
Cozzone A.J.
Nucleotide sequence of the metA gene encoding homoserine trans-succinylase in Escherichia coli.
Nucleic Acids Res.
17
2856-2856
1989
58285
Born T.L.,Blanchard J.S.
Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Escherichia coli metA-encoded homoserine transsuccinylase.
Biochemistry
38
14416-14423
1999
58286
Blattner F.R.,Burland V.D.,Plunkett G. III,Sofia H.J.,Daniels D.L.
Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.
Nucleic Acids Res.
21
5408-5417
1993
58287
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
58288
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
58289
Michaeli S.,Mevarech M.,Ron E.Z.
Regulatory region of the metA gene of Escherichia coli K-12.
J. Bacteriol.
160
1158-1162
1984
58290
Byrne C.R.,Stokes H.W.,Ward K.A.
Nucleotide sequence of the aceB gene encoding malate synthase A in Escherichia coli.
Nucleic Acids Res.
16
9342-9342
1988
58291
Rosen R.,Becher D.,Buettner K.,Biran D.,Hecker M.,Ron E.Z.
Probing the active site of homoserine trans-succinylase.
FEBS Lett.
577
386-392
2004
58292
Coe D.M.,Viola R.E.
Assessing the roles of essential functional groups in the mechanism of homoserine succinyltransferase.
Arch. Biochem. Biophys.
461
211-218
2007
58293
Ziegler K.,Noble S.M.,Mutumanje E.,Bishop B.,Huddler D.P.,Born T.L.
Identification of catalytic cysteine, histidine, and lysine residues in Escherichia coli homoserine transsuccinylase.
Biochemistry
46
2674-2683
2007
58294
Bastard K.,Perret A.,Mariage A.,Bessonnet T.,Pinet-Turpault A.,Petit J.L.,Darii E.,Bazire P.,Vergne-Vaxelaire C.,Brewee C.,Debard A.,Pellouin V.,Besnard-Gonnet M.,Artiguenave F.,Medigue C.,Vallenet D.,Danchin A.,Zaparucha A.,Weissenbach J.,Salanoubat M.,de Berardinis V.
Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis.
Nat. Chem. Biol.
13
858-866
2017
