Sequence of ILVC_IGNAA
EC Number:1.1.1.383
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ketol-acid reductoisomerase [NAD(P)+]
E0SRA9
Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1)
335
37346
Reaction
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD(P)+ = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NAD(P)H + H+
Other sequences found for EC No. 1.1.1.383
General information:
Sequence
0 MAKIYKDEDI SLEPIKNKTI AILGYGSQGR AWALNLRDSG LNVVVGLERQ GDSWRRAIDD
60 GFKPMYTKDA VAIADIIVFL VPDMVQKSLW LNSVKDFMKK GADLVFAHGF NIHFKIIEPP
120 KDSDVYMIAP KSPGPIVRRS YEMGGGVPAL VAVYQNVSGE ALQKALAIAK GIGCARAGVI
180 ESTFKEETET DLFGEQVILV GGIMELIKAS FETLVEEGYQ PEVAYFETVN ELKLIVDLIY
240 EKGLTGMLRA VSDTAKYGGI TVGKFIIDKS VRDKMKIVLE RIRSGEFARE WIKEYERGMP
300 TVFKELSELE GSTIETVGRK LREMMFRGMK QISSH
Download this sequence
in fasta formatDownload all sequences for 1.1.1.383
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
685632
Goker M.,Held B.,Lapidus A.,Nolan M.,Spring S.,Yasawong M.,Lucas S.,Glavina Del Rio T.,Tice H.,Cheng J.F.,Goodwin L.,Tapia R.,Pitluck S.,Liolios K.,Ivanova N.,Mavromatis K.,Mikhailova N.,Pati A.,Chen A.,Palaniappan K.,Brambilla E.,Land M.,Hauser L.,Chang Y.J.,Jeffries C.D.,Brettin T.,Detter J.C.,Han C.,Rohde M.,Sikorski J.,Woyke T.,Bristow J.,Eisen J.A.,Markowitz V.,Hugenholtz P.,Kyrpides N.C.,Klenk H.P.
Complete genome sequence of Ignisphaera aggregans type strain (AQ1.S1).
Stand. Genomic Sci.
3
66-75
2010
685633
Brinkmann-Chen S.,Cahn J.K.,Arnold F.H.
Uncovering rare NADH-preferring ketol-acid reductoisomerases.
Metab. Eng.
26
17-22
2014
685634
Cahn J.K.,Brinkmann-Chen S.,Spatzal T.,Wiig J.A.,Buller A.R.,Einsle O.,Hu Y.,Ribbe M.W.,Arnold F.H.
Cofactor specificity motifs and the induced fit mechanism in class I ketol-acid reductoisomerases.
Biochem. J.
468
475-484
2015
685635
Cahn J.K.,Brinkmann-Chen S.,Buller A.R.,Arnold F.H.
Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases.
Protein Sci.
25
1241-1248
2016
