Sequence of CP4F1_RAT
EC Number:1.14.14.94
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + [reduced NADPH-hemoprotein reductase] + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + [oxidized NADPH-hemoprotein reductase] + H2O
Other sequences found for EC No. 1.14.14.94
General information:
Sequence
0 MSQLSLSWLG LGPEVAFPWQ TLLLFGASWI LAQILTQIYA AYRNFRRLRG FPQPPKRNWL
60 MGHVGMVTPT EQGLKELTRL VGTYPQGFLM WIGPMVPVIT LCHSDIVRSI LNASAAVALK
120 DVIFYTILKP WLGDGLLVSA GDKWSRHRRM LTPAFHFNIL KPYVKIFNDS TNIMHAKWKR
180 LISEGSSRLD MFEHVSLMTL DSLQKCVFSF DSNCQEKSSE YIAAILELSA LVAKRHQQPL
240 LFMDLLYNLT PDGMRFHKAC NLVHEFTDAV IRERRRTLPD QGLDEFLKSK AKSKTLDFID
300 VLLLTKDEDG KELSDEDIRA EADTFMFEGH DTTASGLSWI LYNLANDPEY QERCRQEVQE
360 LLRDRDPEEI EWDDLAQLPF LTMCIKESLR LHPPVTVISR CCTQDILLPD GRTIPKGIIC
420 LISIFGIHHN PSVWPDPEVY NPFRFDPENI KDSSPLAFIP FSAGPRNCIG QTFAMSEMKV
480 ALALTLLRFR LLPDDKEPRR QPELILRAEG GLWLRVEPLT AGAQ
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
783996
Chen L.,Hardwick J.P.
Identification of a new P450 subfamily, CYP4F1, expressed in rat hepatic tumors.
Arch. Biochem. Biophys.
300
18-23
1993
783998
Kikuta Y.,Kusunose E.,Ito M.,Kusunose M.
Purification and characterization of recombinant rat hepatic CYP4F1.
Arch. Biochem. Biophys.
369
193-196
1999
783999
LeBrun L.A.,Xu F.,Kroetz D.L.,Ortiz de Montellano P.R.
Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family.
Biochemistry
41
5931-5937
2002
784000
Xu F.,Falck J.R.,Ortiz de Montellano P.R.,Kroetz D.L.
Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes.
J. Pharmacol. Exp. Ther.
308
887-895
2004
