Sequence of HSAC_MYCTU
EC Number:1.13.11.25
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
P9WNW7
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
300
33582
Reaction
3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2 = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate
Other sequences found for EC No. 1.13.11.25
General information:
Sequence
0 MSIRSLGYLR IEATDMAAWR EYGLKVLGMV EGKGAPEGAL YLRMDDFPAR LVVVPGEHDR
60 LLEAGWECAN AEGLQEIRNR LDLEGTPYKE ATAAELADRR VDEMIRFADP SGNCLEVFHG
120 TALEHRRVVS PYGHRFVTGE QGMGHVVLST RDDAEALHFY RDVLGFRLRD SMRLPPQMVG
180 RPADGPPAWL RFFGCNPRHH SLAFLPMPTS SGIVHLMVEV EQADDVGLCL DRALRRKVPM
240 SATLGRHVND LMLSFYMKTP GGFDIEFGCE GRQVDDRDWI ARESTAVSLW GHDFTVGARG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
810312
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
810313
Kendall S.L.,Withers M.,Soffair C.N.,Moreland N.J.,Gurcha S.,Sidders B.,Frita R.,Ten Bokum A.,Besra G.S.,Lott J.S.,Stoker N.G.
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis.
Mol. Microbiol.
65
684-699
2007
810314
Van der Geize R.,Yam K.,Heuser T.,Wilbrink M.H.,Hara H.,Anderton M.C.,Sim E.,Dijkhuizen L.,Davies J.E.,Mohn W.W.,Eltis L.D.
A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages.
Proc. Natl. Acad. Sci. U.S.A.
104
1947-1952
2007
810315
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
810316
Yam K.C.,D'Angelo I.,Kalscheuer R.,Zhu H.,Wang J.X.,Snieckus V.,Ly L.H.,Converse P.J.,Jacobs W.R. Jr.,Strynadka N.,Eltis L.D.
Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.
PLoS Pathog.
5
0-0
2009
