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Sequence of GSTO1_HUMAN

EC Number:1.8.5.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glutathione dehydrogenase (ascorbate)
P78417
Homo sapiens
241
27566
Reaction
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate
Other sequences found for EC No. 1.8.5.1

General information:

Sequence
show sequence in fasta format
  0 MSGESARSLG KGSAPPGPVP EGSIRIYSMR FCPFAERTRL VLKAKGIRHE VININLKNKP
 60 EWFFKKNPFG LVPVLENSQG QLIYESAITC EYLDEAYPGK KLLPDDPYEK ACQKMILELF
120 SKVPSLVGSF IRSQNKEDYA GLKEEFRKEF TKLEEVLTNK KTTFFGGNSI SMIDYLIWPW
180 FERLEAMKLN ECVDHTPKLK LWMAAMKEDP TVSALLTSEK DWQGFLELYL QNSPEACDYG
240 L
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
935195
Board P.G.,Coggan M.,Chelvanayagam G.,Easteal S.,Jermiin L.S.,Schulte G.K.,Danley D.E.,Hoth L.R.,Griffor M.C.,Kamath A.V.,Rosner M.H.,Chrunyk B.A.,Perregaux D.E.,Gabel C.A.,Geoghegan K.F.,Pandit J.
Identification, characterization, and crystal structure of the Omega class glutathione transferases.
J. Biol. Chem.
275
24798-24806
2000
935196
Yu L.,Kalla K.,Guthrie E.,Vidrine A.,Klimecki W.T.
Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans.
Environ. Health Perspect.
111
1421-1427
2003
935197
Bechtel S.,Rosenfelder H.,Duda A.,Schmidt C.P.,Ernst U.,Wellenreuther R.,Mehrle A.,Schuster C.,Bahr A.,Bloecker H.,Heubner D.,Hoerlein A.,Michel G.,Wedler H.,Koehrer K.,Ottenwaelder B.,Poustka A.,Wiemann S.,Schupp I.
The full-ORF clone resource of the German cDNA consortium.
BMC Genomics
8
399-399
2007
935198
Deloukas P.,Earthrowl M.E.,Grafham D.V.,Rubenfield M.,French L.,Steward C.A.,Sims S.K.,Jones M.C.,Searle S.,Scott C.,Howe K.,Hunt S.E.,Andrews T.D.,Gilbert J.G.R.,Swarbreck D.,Ashurst J.L.,Taylor A.,Battles J.,Bird C.P.,Ainscough R.,Almeida J.P.,Ashwell R.I.S.,Ambrose K.D.,Babbage A.K.,Bagguley C.L.,Bailey J.,Banerjee R.,Bates K.,Beasley H.,Bray-Allen S.,Brown A.J.,Brown J.Y.,Burford D.C.,Burrill W.,Burton J.,Cahill P.,Camire D.,Carter N.P.,Chapman J.C.,Clark S.Y.,Clarke G.,Clee C.M.,Clegg S.,Corby N.,Coulson A.,Dhami P.,Dutta I.,Dunn M.,Faulkner L.,Frankish A.,Frankland J.A.,Garner P.,Garnett J.,Gribble S.,Griffiths C.,Grocock R.,Gustafson E.,Hammond S.,Harley J.L.,Hart E.,Heath P.D.,Ho T.P.,Hopkins B.,Horne J.,Howden P.J.,Huckle E.,Hynds C.,Johnson C.,Johnson D.,Kana A.,Kay M.,Kimberley A.M.,Kershaw J.K.,Kokkinaki M.,Laird G.K.,Lawlor S.,Lee H.M.,Leongamornlert D.A.,Laird G.,Lloyd C.,Lloyd D.M.,Loveland J.,Lovell J.,McLaren S.,McLay K.E.,McMurray A.,Mashreghi-Mohammadi M.,Matthews L.,Milne S.,Nickerson T.,Nguyen M.,Overton-Larty E.,Palmer S.A.,Pearce A.V.,Peck A.I.,Pelan S.,Phillimore B.,Porter K.,Rice C.M.,Rogosin A.,Ross M.T.,Sarafidou T.,Sehra H.K.,Shownkeen R.,Skuce C.D.,Smith M.,Standring L.,Sycamore N.,Tester J.,Thorpe A.,Torcasso W.,Tracey A.,Tromans A.,Tsolas J.,Wall M.,Walsh J.,Wang H.,Weinstock K.,West A.P.,Willey D.L.,Whitehead S.L.,Wilming L.,Wray P.W.,Young L.,Chen Y.,Lovering R.C.,Moschonas N.K.,Siebert R.,Fechtel K.,Bentley D.,Durbin R.M.,Hubbard T.,Doucette-Stamm L.,Beck S.,Smith D.R.,Rogers J.
The DNA sequence and comparative analysis of human chromosome 10.
Nature
429
375-381
2004
935200
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
935201
Hubbard M.J.,McHugh N.J.
Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping.
Electrophoresis
21
3785-3796
2000
935202
Zakharyan R.A.,Sampayo-Reyes A.,Healy S.M.,Tsaprailis G.,Board P.G.,Liebler D.C.,Aposhian H.V.
Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily.
Chem. Res. Toxicol.
14
1051-1057
2001
935203
Board P.G.,Anders M.W.
Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones.
Chem. Res. Toxicol.
20
149-154
2007
935204
Board P.G.,Coggan M.,Cappello J.,Zhou H.,Oakley A.J.,Anders M.W.
S-(4-Nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1.
Anal. Biochem.
374
25-30
2008
935205
Gauci S.,Helbig A.O.,Slijper M.,Krijgsveld J.,Heck A.J.,Mohammed S.
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Anal. Chem.
81
4493-4501
2009
935206
Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science
325
834-840
2009
935207
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
935208
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
935209
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
935210
Zhou H.,Brock J.,Casarotto M.G.,Oakley A.J.,Board P.G.
Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1.
J. Biol. Chem.
286
4271-4279
2011
935211
Whitbread A.K.,Tetlow N.,Eyre H.J.,Sutherland G.R.,Board P.G.
Characterization of the human Omega class glutathione transferase genes and associated polymorphisms.
Pharmacogenetics
13
131-144
2003